Li Y - Search Results

1

A First-in-Human Study of Novel Cereblon Modulator Avadomide (CC-122) in Advanced Malignancies.

Rasco DW, Papadopoulos KP, Pourdehnad M, Gandhi AK, Hagner PR, Li Y, Wei X, Chopra R, Hege K, DiMartino J, Shih K. Rasco DW, et al. Among authors: li y. Clin Cancer Res. 2019 Jan 1;25(1):90-98. doi: 10.1158/1078-0432.CCR-18-1203. Epub 2018 Sep 10. Clin Cancer Res. 2019. PMID: 30201761 Clinical Trial.

2

Pharmacokinetics and pharmacodynamics of nab-paclitaxel in patients with solid tumors: disposition kinetics and pharmacology distinct from solvent-based paclitaxel.

Chen N, Li Y, Ye Y, Palmisano M, Chopra R, Zhou S. Chen N, et al. Among authors: li y. J Clin Pharmacol. 2014 Oct;54(10):1097-107. doi: 10.1002/jcph.304. Epub 2014 Apr 9. J Clin Pharmacol. 2014. PMID: 24719309 Free PMC article.

3

Albumin-bound nanoparticle (nab) paclitaxel exhibits enhanced paclitaxel tissue distribution and tumor penetration.

Chen N, Brachmann C, Liu X, Pierce DW, Dey J, Kerwin WS, Li Y, Zhou S, Hou S, Carleton M, Klinghoffer RA, Palmisano M, Chopra R. Chen N, et al. Among authors: li y. Cancer Chemother Pharmacol. 2015 Oct;76(4):699-712. doi: 10.1007/s00280-015-2833-5. Epub 2015 Aug 1. Cancer Chemother Pharmacol. 2015. PMID: 26231955 Free PMC article.

4

Population pharmacokinetics of pomalidomide.

Li Y, Xu Y, Liu L, Wang X, Palmisano M, Zhou S. Li Y, et al. J Clin Pharmacol. 2015 May;55(5):563-72. doi: 10.1002/jcph.455. Epub 2015 Feb 4. J Clin Pharmacol. 2015. PMID: 25556560 Free PMC article.

5

Exposure-response analysis to assess the concentration-QTc relationship of CC-122.

Li Y, Carayannopoulos LN, Thomas M, Palmisano M, Zhou S. Li Y, et al. Clin Pharmacol. 2016 Sep 9;8:117-25. doi: 10.2147/CPAA.S111867. eCollection 2016. Clin Pharmacol. 2016. PMID: 27672344 Free PMC article.

6

Population Pharmacokinetics and Exposure Response Assessment of CC-292, a Potent BTK Inhibitor, in Patients With Chronic Lymphocytic Leukemia.

Li Y, Ramírez-Valle F, Xue Y, Ventura JI, Gouedard O, Mei J, Takeshita K, Palmisano M, Zhou S. Li Y, et al. J Clin Pharmacol. 2017 Oct;57(10):1279-1289. doi: 10.1002/jcph.923. Epub 2017 May 19. J Clin Pharmacol. 2017. PMID: 28543084 Free PMC article. Clinical Trial.

7

Pomalidomide: evaluation of cytochrome P450 and transporter-mediated drug-drug interaction potential in vitro and in healthy subjects.

Kasserra C, Assaf M, Hoffmann M, Li Y, Liu L, Wang X, Kumar G, Palmisano M. Kasserra C, et al. Among authors: li y. J Clin Pharmacol. 2015 Feb;55(2):168-78. doi: 10.1002/jcph.384. Epub 2014 Sep 7. J Clin Pharmacol. 2015. PMID: 25159194 Clinical Trial.

8

Population pharmacokinetics of pomalidomide in patients with relapsed or refractory multiple myeloma with various degrees of impaired renal function.

Li Y, Wang X, O'Mara E, Dimopoulos MA, Sonneveld P, Weisel KC, Matous J, Siegel DS, Shah JJ, Kueenburg E, Sternas L, Cavanaugh C, Zaki M, Palmisano M, Zhou S. Li Y, et al. Clin Pharmacol. 2017 Nov 8;9:133-145. doi: 10.2147/CPAA.S144606. eCollection 2017. Clin Pharmacol. 2017. PMID: 29184451 Free PMC article.

9

Modeling and simulation to probe the pharmacokinetic disposition of pomalidomide R- and S-enantiomers.

Li Y, Zhou S, Hoffmann M, Kumar G, Palmisano M. Li Y, et al. J Pharmacol Exp Ther. 2014 Aug;350(2):265-72. doi: 10.1124/jpet.114.215251. Epub 2014 May 15. J Pharmacol Exp Ther. 2014. PMID: 24833703

10

Pharmacologic sensitivity of paclitaxel to its delivery vehicles drives distinct clinical outcomes of paclitaxel formulations.

Li Y, Chen N, Palmisano M, Zhou S. Li Y, et al. Mol Pharm. 2015 Apr 6;12(4):1308-17. doi: 10.1021/acs.molpharmaceut.5b00026. Epub 2015 Mar 16. Mol Pharm. 2015. PMID: 25714793

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