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CaMKII inhibition in human primary and pluripotent stem cell-derived chondrocytes modulates effects of TGFβ and BMP through SMAD signaling.
Osteoarthritis Cartilage. 2019 Jan;27(1):158-171. doi: 10.1016/j.joca.2018.08.017. Epub 2018 Sep 8.
Osteoarthritis Cartilage. 2019.
PMID: 30205161
Free PMC article.
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair.
Shkhyan R, Van Handel B, Bogdanov J, Lee S, Yu Y, Scheinberg M, Banks NW, Limfat S, Chernostrik A, Franciozi CE, Alam MP, John V, Wu L, Ferguson GB, Nsair A, Petrigliano FA, Vangsness CT, Vadivel K, Bajaj P, Wang L, Liu NQ, Evseenko D.
Shkhyan R, et al. Among authors: limfat s.
Ann Rheum Dis. 2018 May;77(5):760-769. doi: 10.1136/annrheumdis-2017-212037. Epub 2018 Feb 7.
Ann Rheum Dis. 2018.
PMID: 29436471
Free PMC article.
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Genetic ablation of adenosine receptor A3 results in articular cartilage degeneration.
Shkhyan R, Lee S, Gullo F, Li L, Peleli M, Carlstrom M, Chagin AS, Banks NW, Limfat S, Liu NQ, Evseenko D.
Shkhyan R, et al. Among authors: limfat s.
J Mol Med (Berl). 2018 Oct;96(10):1049-1060. doi: 10.1007/s00109-018-1680-3. Epub 2018 Aug 7.
J Mol Med (Berl). 2018.
PMID: 30088034
Free PMC article.
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Modulation of Hedgehog Signaling by Kappa Opioids to Attenuate Osteoarthritis.
Weber AE, Jalali O, Limfat S, Shkhyan R, Van Der Horst R, Lee S, Lin Y, Li L, Mayer EN, Wang L, Liu NQ, Petrigliano FA, Lieberman JR, Evseenko D.
Weber AE, et al. Among authors: limfat s.
Arthritis Rheumatol. 2020 Aug;72(8):1278-1288. doi: 10.1002/art.41250. Epub 2020 Jun 24.
Arthritis Rheumatol. 2020.
PMID: 32249508
Free PMC article.
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