Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

243 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.
Mori G, Orena BS, Franch C, Mitchenall LA, Godbole AA, Rodrigues L, Aguilar-Pérez C, Zemanová J, Huszár S, Forbak M, Lane TR, Sabbah M, Deboosere N, Frita R, Vandeputte A, Hoffmann E, Russo R, Connell N, Veilleux C, Jha RK, Kumar P, Freundlich JS, Brodin P, Aínsa JA, Nagaraja V, Maxwell A, Mikušová K, Pasca MR, Ekins S. Mori G, et al. Among authors: connell n. Tuberculosis (Edinb). 2018 Sep;112:98-109. doi: 10.1016/j.tube.2018.08.004. Epub 2018 Aug 11. Tuberculosis (Edinb). 2018. PMID: 30205975
A Novel Small-Molecule Inhibitor of the Mycobacterium tuberculosis Demethylmenaquinone Methyltransferase MenG Is Bactericidal to Both Growing and Nutritionally Deprived Persister Cells.
Sukheja P, Kumar P, Mittal N, Li SG, Singleton E, Russo R, Perryman AL, Shrestha R, Awasthi D, Husain S, Soteropoulos P, Brukh R, Connell N, Freundlich JS, Alland D. Sukheja P, et al. Among authors: connell n. mBio. 2017 Feb 14;8(1):e02022-16. doi: 10.1128/mBio.02022-16. mBio. 2017. PMID: 28196957 Free PMC article.
Novel Pyrimidines as Antitubercular Agents.
Inoyama D, Paget SD, Russo R, Kandasamy S, Kumar P, Singleton E, Occi J, Tuckman M, Zimmerman MD, Ho HP, Perryman AL, Dartois V, Connell N, Freundlich JS. Inoyama D, et al. Among authors: connell n. Antimicrob Agents Chemother. 2018 Feb 23;62(3):e02063-17. doi: 10.1128/AAC.02063-17. Print 2018 Mar. Antimicrob Agents Chemother. 2018. PMID: 29311070 Free PMC article.
Optimization of N-benzyl-5-nitrofuran-2-carboxamide as an antitubercular agent.
Gallardo-Macias R, Kumar P, Jaskowski M, Richmann T, Shrestha R, Russo R, Singleton E, Zimmerman MD, Ho HP, Dartois V, Connell N, Alland D, Freundlich JS. Gallardo-Macias R, et al. Among authors: connell n. Bioorg Med Chem Lett. 2019 Feb 15;29(4):601-606. doi: 10.1016/j.bmcl.2018.12.053. Epub 2018 Dec 24. Bioorg Med Chem Lett. 2019. PMID: 30600207 Free PMC article.
Antitubercular Triazines: Optimization and Intrabacterial Metabolism.
Wang X, Inoyama D, Russo R, Li SG, Jadhav R, Stratton TP, Mittal N, Bilotta JA, Singleton E, Kim T, Paget SD, Pottorf RS, Ahn YM, Davila-Pagan A, Kandasamy S, Grady C, Hussain S, Soteropoulos P, Zimmerman MD, Ho HP, Park S, Dartois V, Ekins S, Connell N, Kumar P, Freundlich JS. Wang X, et al. Among authors: connell n. Cell Chem Biol. 2020 Feb 20;27(2):172-185.e11. doi: 10.1016/j.chembiol.2019.10.010. Epub 2019 Nov 8. Cell Chem Biol. 2020. PMID: 31711854 Free PMC article.
Naïve Bayesian Models for Vero Cell Cytotoxicity.
Perryman AL, Patel JS, Russo R, Singleton E, Connell N, Ekins S, Freundlich JS. Perryman AL, et al. Among authors: connell n. Pharm Res. 2018 Jun 29;35(9):170. doi: 10.1007/s11095-018-2439-9. Pharm Res. 2018. PMID: 29959603 Free PMC article.
Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
Kumar P, Capodagli GC, Awasthi D, Shrestha R, Maharaja K, Sukheja P, Li SG, Inoyama D, Zimmerman M, Ho Liang HP, Sarathy J, Mina M, Rasic G, Russo R, Perryman AL, Richmann T, Gupta A, Singleton E, Verma S, Husain S, Soteropoulos P, Wang Z, Morris R, Porter G, Agnihotri G, Salgame P, Ekins S, Rhee KY, Connell N, Dartois V, Neiditch MB, Freundlich JS, Alland D. Kumar P, et al. Among authors: connell n. mBio. 2018 Dec 18;9(6):e02101-17. doi: 10.1128/mBio.02101-17. mBio. 2018. PMID: 30563908 Free PMC article.
A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Inoyama D, Awasthi D, Capodagli GC, Tsotetsi K, Sukheja P, Zimmerman M, Li SG, Jadhav R, Russo R, Wang X, Grady C, Richmann T, Shrestha R, Li L, Ahn YM, Ho Liang HP, Mina M, Park S, Perlin DS, Connell N, Dartois V, Alland D, Neiditch MB, Kumar P, Freundlich JS. Inoyama D, et al. Among authors: connell n. Cell Chem Biol. 2020 May 21;27(5):560-570.e10. doi: 10.1016/j.chembiol.2020.02.007. Epub 2020 Mar 19. Cell Chem Biol. 2020. PMID: 32197094 Free PMC article.
Addressing the Metabolic Stability of Antituberculars through Machine Learning.
Stratton TP, Perryman AL, Vilchèze C, Russo R, Li SG, Patel JS, Singleton E, Ekins S, Connell N, Jacobs WR Jr, Freundlich JS. Stratton TP, et al. Among authors: connell n. ACS Med Chem Lett. 2017 Sep 14;8(10):1099-1104. doi: 10.1021/acsmedchemlett.7b00299. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057058 Free PMC article.
243 results