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The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.
Mori G, Orena BS, Franch C, Mitchenall LA, Godbole AA, Rodrigues L, Aguilar-Pérez C, Zemanová J, Huszár S, Forbak M, Lane TR, Sabbah M, Deboosere N, Frita R, Vandeputte A, Hoffmann E, Russo R, Connell N, Veilleux C, Jha RK, Kumar P, Freundlich JS, Brodin P, Aínsa JA, Nagaraja V, Maxwell A, Mikušová K, Pasca MR, Ekins S. Mori G, et al. Among authors: freundlich js. Tuberculosis (Edinb). 2018 Sep;112:98-109. doi: 10.1016/j.tube.2018.08.004. Epub 2018 Aug 11. Tuberculosis (Edinb). 2018. PMID: 30205975
Dynamic PET Reveals Compartmentalized Brain and Lung Tissue Antibiotic Exposures.
Jain S, Chen X, Arun B, Meza ON, Sarhan M, Singh M, Jeon B, Mane K, Shah M, Tucker E, Carroll L, Freundlich J, Peloquin C, Ivaturi V. Jain S, et al. Res Sq [Preprint]. 2024 Mar 21:rs.3.rs-4096014. doi: 10.21203/rs.3.rs-4096014/v1. Res Sq. 2024. Update in: Nat Commun. 2024 Aug 14;15(1):6657. doi: 10.1038/s41467-024-50989-4 PMID: 38562706 Free PMC article. Updated. Preprint.
Computational models for tuberculosis drug discovery.
Ekins S, Freundlich JS. Ekins S, et al. Among authors: freundlich js. Methods Mol Biol. 2013;993:245-62. doi: 10.1007/978-1-62703-342-8_16. Methods Mol Biol. 2013. PMID: 23568475 Review.
93 results