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The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.
Mori G, Orena BS, Franch C, Mitchenall LA, Godbole AA, Rodrigues L, Aguilar-Pérez C, Zemanová J, Huszár S, Forbak M, Lane TR, Sabbah M, Deboosere N, Frita R, Vandeputte A, Hoffmann E, Russo R, Connell N, Veilleux C, Jha RK, Kumar P, Freundlich JS, Brodin P, Aínsa JA, Nagaraja V, Maxwell A, Mikušová K, Pasca MR, Ekins S. Mori G, et al. Among authors: rodrigues l. Tuberculosis (Edinb). 2018 Sep;112:98-109. doi: 10.1016/j.tube.2018.08.004. Epub 2018 Aug 11. Tuberculosis (Edinb). 2018. PMID: 30205975
Antituberculosis drugs: reducing efflux=increasing activity.
Rodrigues L, Parish T, Balganesh M, Ainsa JA. Rodrigues L, et al. Drug Discov Today. 2017 Mar;22(3):592-599. doi: 10.1016/j.drudis.2017.01.002. Epub 2017 Jan 13. Drug Discov Today. 2017. PMID: 28089787 Review.
Synergy between Circular Bacteriocin AS-48 and Ethambutol against Mycobacterium tuberculosis.
Aguilar-Pérez C, Gracia B, Rodrigues L, Vitoria A, Cebrián R, Deboosère N, Song OR, Brodin P, Maqueda M, Aínsa JA. Aguilar-Pérez C, et al. Among authors: rodrigues l. Antimicrob Agents Chemother. 2018 Aug 27;62(9):e00359-18. doi: 10.1128/AAC.00359-18. Print 2018 Sep. Antimicrob Agents Chemother. 2018. PMID: 29987141 Free PMC article.
Measuring Efflux and Permeability in Mycobacteria.
Rodrigues L, Aínsa JA, Viveiros M. Rodrigues L, et al. Methods Mol Biol. 2021;2314:231-245. doi: 10.1007/978-1-0716-1460-0_9. Methods Mol Biol. 2021. PMID: 34235655
Measuring efflux and permeability in mycobacteria.
Rodrigues L, Viveiros M, Aínsa JA. Rodrigues L, et al. Methods Mol Biol. 2015;1285:227-39. doi: 10.1007/978-1-4939-2450-9_13. Methods Mol Biol. 2015. PMID: 25779319
Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.
Singh V, Dhar N, Pató J, Kolly GS, Korduláková J, Forbak M, Evans JC, Székely R, Rybniker J, Palčeková Z, Zemanová J, Santi I, Signorino-Gelo F, Rodrigues L, Vocat A, Covarrubias AS, Rengifo MG, Johnsson K, Mowbray S, Buechler J, Delorme V, Brodin P, Knott GW, Aínsa JA, Warner DF, Kéri G, Mikušová K, McKinney JD, Cole ST, Mizrahi V, Hartkoorn RC. Singh V, et al. Among authors: rodrigues l. Mol Microbiol. 2017 Jan;103(1):13-25. doi: 10.1111/mmi.13535. Epub 2016 Oct 29. Mol Microbiol. 2017. PMID: 27677649 Free article.
2,770 results