Sabbah M - Search Results

1

The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.

Mori G, Orena BS, Franch C, Mitchenall LA, Godbole AA, Rodrigues L, Aguilar-Pérez C, Zemanová J, Huszár S, Forbak M, Lane TR, Sabbah M, Deboosere N, Frita R, Vandeputte A, Hoffmann E, Russo R, Connell N, Veilleux C, Jha RK, Kumar P, Freundlich JS, Brodin P, Aínsa JA, Nagaraja V, Maxwell A, Mikušová K, Pasca MR, Ekins S. Mori G, et al. Among authors: sabbah m. Tuberculosis (Edinb). 2018 Sep;112:98-109. doi: 10.1016/j.tube.2018.08.004. Epub 2018 Aug 11. Tuberculosis (Edinb). 2018. PMID: 30205975

2

Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors.

Sabbah M, Mendes V, Vistal RG, Dias DMG, Záhorszká M, Mikušová K, Korduláková J, Coyne AG, Blundell TL, Abell C. Sabbah M, et al. J Med Chem. 2020 May 14;63(9):4749-4761. doi: 10.1021/acs.jmedchem.0c00007. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32240584 Free PMC article.

3

Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.

Trapero A, Pacitto A, Singh V, Sabbah M, Coyne AG, Mizrahi V, Blundell TL, Ascher DB, Abell C. Trapero A, et al. Among authors: sabbah m. J Med Chem. 2018 Apr 12;61(7):2806-2822. doi: 10.1021/acs.jmedchem.7b01622. Epub 2018 Mar 23. J Med Chem. 2018. PMID: 29547284 Free PMC article.

4

Correction to Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors.

Sabbah M, Mendes V, Vistal RG, Dias DMG, Záhorszká M, Mikušová K, Korduláková J, Coyne AG, Blundell TL, Abell C. Sabbah M, et al. J Med Chem. 2020 Aug 13;63(15):8650. doi: 10.1021/acs.jmedchem.0c01187. Epub 2020 Jul 22. J Med Chem. 2020. PMID: 32697583 Free PMC article. No abstract available.

5

LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones.

Soulère L, Sabbah M, Fontaine F, Queneau Y, Doutheau A. Soulère L, et al. Among authors: sabbah m. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4355-8. doi: 10.1016/j.bmcl.2010.06.081. Epub 2010 Jun 17. Bioorg Med Chem Lett. 2010. PMID: 20615699

6

Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach.

Mugumbate G, Mendes V, Blaszczyk M, Sabbah M, Papadatos G, Lelievre J, Ballell L, Barros D, Abell C, Blundell TL, Overington JP. Mugumbate G, et al. Among authors: sabbah m. Front Pharmacol. 2017 Sep 26;8:681. doi: 10.3389/fphar.2017.00681. eCollection 2017. Front Pharmacol. 2017. PMID: 29018348 Free PMC article.

7

Synthesis and biological evaluation of new N-acyl-homoserine-lactone analogues, based on triazole and tetrazole scaffolds, acting as LuxR-dependent quorum sensing modulators.

Sabbah M, Fontaine F, Grand L, Boukraa M, Efrit ML, Doutheau A, Soulère L, Queneau Y. Sabbah M, et al. Bioorg Med Chem. 2012 Aug 1;20(15):4727-36. doi: 10.1016/j.bmc.2012.06.007. Epub 2012 Jun 9. Bioorg Med Chem. 2012. PMID: 22748707

8

LuxR dependent quorum sensing inhibition by N,N'-disubstituted imidazolium salts.

Sabbah M, Soulère L, Reverchon S, Queneau Y, Doutheau A. Sabbah M, et al. Bioorg Med Chem. 2011 Aug 15;19(16):4868-75. doi: 10.1016/j.bmc.2011.06.075. Epub 2011 Jun 29. Bioorg Med Chem. 2011. PMID: 21782453

9

N,N'-alkylated Imidazolium-derivatives act as quorum-sensing inhibitors targeting the Pectobacterium atrosepticum-induced symptoms on potato tubers.

des Essarts YR, Sabbah M, Comte A, Soulère L, Queneau Y, Dessaux Y, Hélias V, Faure D. des Essarts YR, et al. Among authors: sabbah m. Int J Mol Sci. 2013 Oct 8;14(10):19976-86. doi: 10.3390/ijms141019976. Int J Mol Sci. 2013. PMID: 24108370 Free PMC article.

10

AHL-dependent quorum sensing inhibition: synthesis and biological evaluation of α-(N-alkyl-carboxamide)-γ-butyrolactones and α-(N-alkyl-sulfonamide)-γ-butyrolactones.

Boukraa M, Sabbah M, Soulère L, El Efrit ML, Queneau Y, Doutheau A. Boukraa M, et al. Among authors: sabbah m. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6876-9. doi: 10.1016/j.bmcl.2011.09.010. Epub 2011 Sep 10. Bioorg Med Chem Lett. 2011. PMID: 21974956

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