Iwatsubo T - Search Results

1

LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis.

Eguchi T, Kuwahara T, Sakurai M, Komori T, Fujimoto T, Ito G, Yoshimura SI, Harada A, Fukuda M, Koike M, Iwatsubo T. Eguchi T, et al. Among authors: iwatsubo t. Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):E9115-E9124. doi: 10.1073/pnas.1812196115. Epub 2018 Sep 12. Proc Natl Acad Sci U S A. 2018. PMID: 30209220 Free PMC article.

2

Familial Parkinson mutant alpha-synuclein causes dopamine neuron dysfunction in transgenic Caenorhabditis elegans.

Kuwahara T, Koyama A, Gengyo-Ando K, Masuda M, Kowa H, Tsunoda M, Mitani S, Iwatsubo T. Kuwahara T, et al. Among authors: iwatsubo t. J Biol Chem. 2006 Jan 6;281(1):334-40. doi: 10.1074/jbc.M504860200. Epub 2005 Oct 31. J Biol Chem. 2006. PMID: 16260788 Free article.

3

Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1.

Ito G, Ariga H, Nakagawa Y, Iwatsubo T. Ito G, et al. Among authors: iwatsubo t. Biochem Biophys Res Commun. 2006 Jan 13;339(2):667-72. doi: 10.1016/j.bbrc.2005.11.058. Epub 2005 Nov 18. Biochem Biophys Res Commun. 2006. PMID: 16316629

4

[Pathogenesis of Parkinson's disease: implications from familial Parkinson's disease].

Iwatsubo T, Ito G, Takatori S, Hannno Y, Kuwahara T. Iwatsubo T, et al. Rinsho Shinkeigaku. 2005 Nov;45(11):899-901. Rinsho Shinkeigaku. 2005. PMID: 16447757 Review. Japanese.

5

LRRK2 in Parkinson's disease and dementia with Lewy bodies.

Zhu X, Babar A, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Perry G, Chen SG. Zhu X, et al. Among authors: iwatsubo t. Mol Neurodegener. 2006 Nov 30;1:17. doi: 10.1186/1750-1326-1-17. Mol Neurodegener. 2006. PMID: 17137507 Free PMC article.

6

GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease.

Ito G, Okai T, Fujino G, Takeda K, Ichijo H, Katada T, Iwatsubo T. Ito G, et al. Among authors: iwatsubo t. Biochemistry. 2007 Feb 6;46(5):1380-8. doi: 10.1021/bi061960m. Biochemistry. 2007. PMID: 17260967

7

Analysis of the adrenal gland is useful for evaluating pathology of the peripheral autonomic nervous system in lewy body disease.

Fumimura Y, Ikemura M, Saito Y, Sengoku R, Kanemaru K, Sawabe M, Arai T, Ito G, Iwatsubo T, Fukayama M, Mizusawa H, Murayama S. Fumimura Y, et al. Among authors: iwatsubo t. J Neuropathol Exp Neurol. 2007 May;66(5):354-62. doi: 10.1097/nen.0b013e3180517454. J Neuropathol Exp Neurol. 2007. PMID: 17483692

8

Proteomics of Caenorhabditis elegans over-expressing human alpha-synuclein analyzed by fluorogenic derivatization-liquid chromatography/tandem mass spectrometry: identification of actin and several ribosomal proteins as negative markers at early Parkinson's disease stages.

Ichibangase T, Saimaru H, Takamura N, Kuwahara T, Koyama A, Iwatsubo T, Imai K. Ichibangase T, et al. Among authors: iwatsubo t. Biomed Chromatogr. 2008 Mar;22(3):232-4. doi: 10.1002/bmc.931. Biomed Chromatogr. 2008. PMID: 17939164

9

Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.

Takatori S, Ito G, Iwatsubo T. Takatori S, et al. Among authors: iwatsubo t. Neurosci Lett. 2008 Jan 3;430(1):13-7. doi: 10.1016/j.neulet.2007.10.019. Epub 2007 Nov 26. Neurosci Lett. 2008. PMID: 18031932

10

Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease.

Kaneko H, Kakita A, Kasuga K, Nozaki H, Ishikawa A, Miyashita A, Kuwano R, Ito G, Iwatsubo T, Takahashi H, Nishizawa M, Onodera O, Sisodia SS, Ikeuchi T. Kaneko H, et al. Among authors: iwatsubo t. J Neurosci. 2007 Nov 28;27(48):13092-7. doi: 10.1523/JNEUROSCI.4244-07.2007. J Neurosci. 2007. PMID: 18045903 Free PMC article.

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