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IL-17A is functionally relevant and a potential therapeutic target in bullous pemphigoid.
Chakievska L, Holtsche MM, Künstner A, Goletz S, Petersen BS, Thaci D, Ibrahim SM, Ludwig RJ, Franke A, Sadik CD, Zillikens D, Hölscher C, Busch H, Schmidt E. Chakievska L, et al. Among authors: holscher c. J Autoimmun. 2019 Jan;96:104-112. doi: 10.1016/j.jaut.2018.09.003. Epub 2018 Sep 13. J Autoimmun. 2019. PMID: 30219389 Free article.
IgG Fc sialylation is regulated during the germinal center reaction following immunization with different adjuvants.
Bartsch YC, Eschweiler S, Leliavski A, Lunding HB, Wagt S, Petry J, Lilienthal GM, Rahmöller J, de Haan N, Hölscher A, Erapaneedi R, Giannou AD, Aly L, Sato R, de Neef LA, Winkler A, Braumann D, Hobusch J, Kuhnigk K, Krémer V, Steinhaus M, Blanchard V, Gemoll T, Habermann JK, Collin M, Salinas G, Manz RA, Fukuyama H, Korn T, Waisman A, Yogev N, Huber S, Rabe B, Rose-John S, Busch H, Berberich-Siebelt F, Hölscher C, Wuhrer M, Ehlers M. Bartsch YC, et al. Among authors: holscher c, holscher a. J Allergy Clin Immunol. 2020 Sep;146(3):652-666.e11. doi: 10.1016/j.jaci.2020.04.059. Epub 2020 May 21. J Allergy Clin Immunol. 2020. PMID: 32445838 Free article.
Interleukin-23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin-17A.
Ritter K, Behrends J, Erdmann H, Rousseau J, Hölscher A, Volz J, Prinz I, Lindenstrøm T, Hölscher C. Ritter K, et al. Among authors: holscher c, holscher a. J Mol Med (Berl). 2021 Nov;99(11):1585-1602. doi: 10.1007/s00109-021-02100-3. Epub 2021 Aug 5. J Mol Med (Berl). 2021. PMID: 34351501 Free PMC article.
The increased protection and pathology in Mycobacterium tuberculosis-infected IL-27R-alpha-deficient mice is supported by IL-17A and is associated with the IL-17A-induced expansion of multifunctional T cells.
Erdmann H, Behrends J, Ritter K, Hölscher A, Volz J, Rosenkrands I, Hölscher C. Erdmann H, et al. Among authors: holscher c, holscher a. Mucosal Immunol. 2018 Jul;11(4):1168-1180. doi: 10.1038/s41385-018-0026-3. Epub 2018 May 4. Mucosal Immunol. 2018. PMID: 29728641 Free article.
432 results