Schwabe JWR - Search Results

1

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.

Zhang T, Wei G, Millard CJ, Fischer R, Konietzny R, Kessler BM, Schwabe JWR, Brockdorff N. Zhang T, et al. Among authors: schwabe jwr. Nat Commun. 2018 Sep 18;9(1):3798. doi: 10.1038/s41467-018-06235-9. Nat Commun. 2018. PMID: 30228260 Free PMC article.

2

Structural insights into the complex of oncogenic KRas4B^G12V and Rgl2, a RalA/B activator.

Tariq M, Ikeya T, Togashi N, Fairall L, Kamei S, Mayooramurugan S, Abbott LR, Hasan A, Bueno-Alejo C, Sukegawa S, Romartinez-Alonso B, Muro Campillo MA, Hudson AJ, Ito Y, Schwabe JW, Dominguez C, Tanaka K. Tariq M, et al. Life Sci Alliance. 2023 Oct 13;7(1):e202302080. doi: 10.26508/lsa.202302080. Print 2024 Jan. Life Sci Alliance. 2023. PMID: 37833074 Free PMC article.

3

Class I HDACs share a common mechanism of regulation by inositol phosphates.

Millard CJ, Watson PJ, Celardo I, Gordiyenko Y, Cowley SM, Robinson CV, Fairall L, Schwabe JW. Millard CJ, et al. Mol Cell. 2013 Jul 11;51(1):57-67. doi: 10.1016/j.molcel.2013.05.020. Epub 2013 Jun 20. Mol Cell. 2013. PMID: 23791785 Free PMC article.

4

An evolving understanding of nuclear receptor coregulator proteins.

Millard CJ, Watson PJ, Fairall L, Schwabe JW. Millard CJ, et al. J Mol Endocrinol. 2013 Nov 7;51(3):T23-36. doi: 10.1530/JME-13-0227. Print 2013 Dec. J Mol Endocrinol. 2013. PMID: 24203923 Free PMC article. Review.

5

Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells.

Jamaladdin S, Kelly RD, O'Regan L, Dovey OM, Hodson GE, Millard CJ, Portolano N, Fry AM, Schwabe JW, Cowley SM. Jamaladdin S, et al. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9840-5. doi: 10.1073/pnas.1321330111. Epub 2014 Jun 23. Proc Natl Acad Sci U S A. 2014. PMID: 24958871 Free PMC article.

6

Recombinant protein expression for structural biology in HEK 293F suspension cells: a novel and accessible approach.

Portolano N, Watson PJ, Fairall L, Millard CJ, Milano CP, Song Y, Cowley SM, Schwabe JW. Portolano N, et al. J Vis Exp. 2014 Oct 16;(92):e51897. doi: 10.3791/51897. J Vis Exp. 2014. PMID: 25349981 Free PMC article.

7

Towards an understanding of the structure and function of MTA1.

Millard CJ, Fairall L, Schwabe JW. Millard CJ, et al. Cancer Metastasis Rev. 2014 Dec;33(4):857-67. doi: 10.1007/s10555-014-9513-5. Cancer Metastasis Rev. 2014. PMID: 25352341 Free PMC article. Review.

8

Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.

Itoh T, Fairall L, Muskett FW, Milano CP, Watson PJ, Arnaudo N, Saleh A, Millard CJ, El-Mezgueldi M, Martino F, Schwabe JW. Itoh T, et al. Nucleic Acids Res. 2015 Feb 27;43(4):2033-44. doi: 10.1093/nar/gkv068. Epub 2015 Feb 4. Nucleic Acids Res. 2015. PMID: 25653165 Free PMC article.

9

The structure of the core NuRD repression complex provides insights into its interaction with chromatin.

Millard CJ, Varma N, Saleh A, Morris K, Watson PJ, Bottrill AR, Fairall L, Smith CJ, Schwabe JW. Millard CJ, et al. Elife. 2016 Apr 21;5:e13941. doi: 10.7554/eLife.13941. Elife. 2016. PMID: 27098840 Free PMC article.

10

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.

Watson PJ, Millard CJ, Riley AM, Robertson NS, Wright LC, Godage HY, Cowley SM, Jamieson AG, Potter BV, Schwabe JW. Watson PJ, et al. Nat Commun. 2016 Apr 25;7:11262. doi: 10.1038/ncomms11262. Nat Commun. 2016. PMID: 27109927 Free PMC article.

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