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Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability.
Bokhari A, Jonchere V, Lagrange A, Bertrand R, Svrcek M, Marisa L, Buhard O, Greene M, Demidova A, Jia J, Adriaenssens E, Chassat T, Biard DS, Flejou JF, Lejeune F, Duval A, Collura A. Bokhari A, et al. Among authors: lejeune f. Oncogenesis. 2018 Sep 19;7(9):70. doi: 10.1038/s41389-018-0079-x. Oncogenesis. 2018. PMID: 30228267 Free PMC article.
Rescue of nonsense mutations by amlexanox in human cells.
Gonzalez-Hilarion S, Beghyn T, Jia J, Debreuck N, Berte G, Mamchaoui K, Mouly V, Gruenert DC, Déprez B, Lejeune F. Gonzalez-Hilarion S, et al. Among authors: lejeune f. Orphanet J Rare Dis. 2012 Aug 31;7:58. doi: 10.1186/1750-1172-7-58. Orphanet J Rare Dis. 2012. PMID: 22938201 Free PMC article.
Caspases shutdown nonsense-mediated mRNA decay during apoptosis.
Jia J, Furlan A, Gonzalez-Hilarion S, Leroy C, Gruenert DC, Tulasne D, Lejeune F. Jia J, et al. Among authors: lejeune f. Cell Death Differ. 2015 Nov;22(11):1754-63. doi: 10.1038/cdd.2015.18. Epub 2015 Mar 6. Cell Death Differ. 2015. PMID: 25744026 Free PMC article.
2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations.
Trzaska C, Amand S, Bailly C, Leroy C, Marchand V, Duvernois-Berthet E, Saliou JM, Benhabiles H, Werkmeister E, Chassat T, Guilbert R, Hannebique D, Mouray A, Copin MC, Moreau PA, Adriaenssens E, Kulozik A, Westhof E, Tulasne D, Motorin Y, Rebuffat S, Lejeune F. Trzaska C, et al. Among authors: lejeune f. Nat Commun. 2020 Mar 20;11(1):1509. doi: 10.1038/s41467-020-15140-z. Nat Commun. 2020. PMID: 32198346 Free PMC article.
A role for AKT1 in nonsense-mediated mRNA decay.
Palma M, Leroy C, Salomé-Desnoulez S, Werkmeister E, Kong R, Mongy M, Le Hir H, Lejeune F. Palma M, et al. Among authors: lejeune f. Nucleic Acids Res. 2021 Nov 8;49(19):11022-11037. doi: 10.1093/nar/gkab882. Nucleic Acids Res. 2021. PMID: 34634811 Free PMC article.
552 results