Ralph SA - Search Results

1

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome.

Bridgford JL, Xie SC, Cobbold SA, Pasaje CFA, Herrmann S, Yang T, Gillett DL, Dick LR, Ralph SA, Dogovski C, Spillman NJ, Tilley L. Bridgford JL, et al. Among authors: ralph sa. Nat Commun. 2018 Sep 18;9(1):3801. doi: 10.1038/s41467-018-06221-1. Nat Commun. 2018. PMID: 30228310 Free PMC article.

2

Determination of protein subcellular localization in apicomplexan parasites.

Woodcroft BJ, McMillan PJ, Dekiwadia C, Tilley L, Ralph SA. Woodcroft BJ, et al. Among authors: ralph sa. Trends Parasitol. 2012 Dec;28(12):546-54. doi: 10.1016/j.pt.2012.08.008. Epub 2012 Sep 17. Trends Parasitol. 2012. PMID: 22995720 Review.

3

Aminoacyl-tRNA synthetases as drug targets in eukaryotic parasites.

Pham JS, Dawson KL, Jackson KE, Lim EE, Pasaje CF, Turner KE, Ralph SA. Pham JS, et al. Among authors: ralph sa. Int J Parasitol Drugs Drug Resist. 2013 Nov 11;4(1):1-13. doi: 10.1016/j.ijpddr.2013.10.001. eCollection 2014 Apr. Int J Parasitol Drugs Drug Resist. 2013. PMID: 24596663 Free PMC article. Review.

4

Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs.

Cobbold SA, Chua HH, Nijagal B, Creek DJ, Ralph SA, McConville MJ. Cobbold SA, et al. Among authors: ralph sa. J Infect Dis. 2016 Jan 15;213(2):276-86. doi: 10.1093/infdis/jiv372. Epub 2015 Jul 6. J Infect Dis. 2016. PMID: 26150544

5

Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum.

Pasaje CF, Cheung V, Kennedy K, Lim EE, Baell JB, Griffin MD, Ralph SA. Pasaje CF, et al. Among authors: ralph sa. Sci Rep. 2016 Jun 9;6:27531. doi: 10.1038/srep27531. Sci Rep. 2016. PMID: 27277538 Free PMC article.

6

Artemisinin Action and Resistance in Plasmodium falciparum.

Tilley L, Straimer J, Gnädig NF, Ralph SA, Fidock DA. Tilley L, et al. Among authors: ralph sa. Trends Parasitol. 2016 Sep;32(9):682-696. doi: 10.1016/j.pt.2016.05.010. Epub 2016 Jun 9. Trends Parasitol. 2016. PMID: 27289273 Free PMC article. Review.

7

Large scale production of a mammalian cell derived quadrivalent hepatitis C virus like particle vaccine.

Earnest-Silveira L, Christiansen D, Herrmann S, Ralph SA, Das S, Gowans EJ, Torresi J. Earnest-Silveira L, et al. Among authors: ralph sa. J Virol Methods. 2016 Oct;236:87-92. doi: 10.1016/j.jviromet.2016.06.012. Epub 2016 Jun 29. J Virol Methods. 2016. PMID: 27373602

8

Metabolomics-Based Screening of the Malaria Box Reveals both Novel and Established Mechanisms of Action.

Creek DJ, Chua HH, Cobbold SA, Nijagal B, MacRae JI, Dickerman BK, Gilson PR, Ralph SA, McConville MJ. Creek DJ, et al. Among authors: ralph sa. Antimicrob Agents Chemother. 2016 Oct 21;60(11):6650-6663. doi: 10.1128/AAC.01226-16. Print 2016 Nov. Antimicrob Agents Chemother. 2016. PMID: 27572396 Free PMC article.

9

Targeting Protein Translation in Organelles of the Apicomplexa.

Goodman CD, Pasaje CFA, Kennedy K, McFadden GI, Ralph SA. Goodman CD, et al. Among authors: ralph sa. Trends Parasitol. 2016 Dec;32(12):953-965. doi: 10.1016/j.pt.2016.09.011. Epub 2016 Oct 25. Trends Parasitol. 2016. PMID: 27793563 Review.

10

Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking.

Kennedy K, Cobbold SA, Hanssen E, Birnbaum J, Spillman NJ, McHugh E, Brown H, Tilley L, Spielmann T, McConville MJ, Ralph SA. Kennedy K, et al. Among authors: ralph sa. PLoS Biol. 2019 Jul 18;17(7):e3000376. doi: 10.1371/journal.pbio.3000376. eCollection 2019 Jul. PLoS Biol. 2019. PMID: 31318858 Free PMC article.

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