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The physiological role of drug transporters.
Liang Y, Li S, Chen L. Liang Y, et al. Among authors: chen l. Protein Cell. 2015 May;6(5):334-50. doi: 10.1007/s13238-015-0148-2. Epub 2015 Mar 24. Protein Cell. 2015. PMID: 25797421 Free PMC article. Review.
A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.
Liu P, Ge M, Hu J, Li X, Che L, Sun K, Cheng L, Huang Y, Pilo MG, Cigliano A, Pes GM, Pascale RM, Brozzetti S, Vidili G, Porcu A, Cossu A, Palmieri G, Sini MC, Ribback S, Dombrowski F, Tao J, Calvisi DF, Chen L, Chen X. Liu P, et al. Among authors: chen l, chen x. Hepatology. 2017 Jul;66(1):167-181. doi: 10.1002/hep.29183. Epub 2017 May 22. Hepatology. 2017. PMID: 28370287 Free PMC article.
Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L. Cheng L, et al. Among authors: chen l. Arch Toxicol. 2018 Jan;92(1):469-485. doi: 10.1007/s00204-017-2048-0. Epub 2017 Sep 4. Arch Toxicol. 2018. PMID: 28871336 Free PMC article.
Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue.
Song W, Luo Q, Zhang Y, Zhou L, Liu Y, Ma Z, Guo J, Huang Y, Cheng L, Meng Z, Li Z, Zhang B, Li S, Yee SW, Fan H, Li P, Giacomini KM, Chen L. Song W, et al. Among authors: chen l. PLoS Biol. 2019 Jan 17;17(1):e2006571. doi: 10.1371/journal.pbio.2006571. eCollection 2019 Jan. PLoS Biol. 2019. PMID: 30653498 Free PMC article.
mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis.
Li C, Chen H, Lan Z, He S, Chen R, Wang F, Liu Z, Li K, Cheng L, Liu Y, Sun K, Wan X, Chen X, Peng H, Li L, Zhang Y, Jing Y, Huang M, Wang Y, Wang Y, Jiang J, Zha X, Chen L, Zhang H. Li C, et al. Among authors: chen l, chen r, chen h, chen x. Cell Death Differ. 2019 Oct;26(10):2015-2028. doi: 10.1038/s41418-019-0274-0. Epub 2019 Feb 13. Cell Death Differ. 2019. PMID: 30760873 Free PMC article.
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