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Page 1
Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice.
Focke C, Blume T, Zott B, Shi Y, Deussing M, Peters F, Schmidt C, Kleinberger G, Lindner S, Gildehaus FJ, Beyer L, von Ungern-Sternberg B, Bartenstein P, Ozmen L, Baumann K, Dorostkar MM, Haass C, Adelsberger H, Herms J, Rominger A, Brendel M. Focke C, et al. Among authors: zott b. J Nucl Med. 2019 Apr;60(4):548-554. doi: 10.2967/jnumed.118.217703. Epub 2018 Sep 27. J Nucl Med. 2019. PMID: 30262517 Free article.
BACE inhibition-dependent repair of Alzheimer's pathophysiology.
Keskin AD, Kekuš M, Adelsberger H, Neumann U, Shimshek DR, Song B, Zott B, Peng T, Förstl H, Staufenbiel M, Nelken I, Sakmann B, Konnerth A, Busche MA. Keskin AD, et al. Among authors: zott b. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8631-8636. doi: 10.1073/pnas.1708106114. Epub 2017 Jul 24. Proc Natl Acad Sci U S A. 2017. PMID: 28739891 Free PMC article.
Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice.
Biechele G, Wind K, Blume T, Sacher C, Beyer L, Eckenweber F, Franzmeier N, Ewers M, Zott B, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Tahirovic S, Willem M, Bartenstein P, Cumming P, Rominger A, Herms J, Brendel M. Biechele G, et al. Among authors: zott b. Neuroimage. 2021 Apr 15;230:117707. doi: 10.1016/j.neuroimage.2020.117707. Epub 2020 Dec 29. Neuroimage. 2021. PMID: 33385560 Free article.
Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation.
Biechele G, Blume T, Deussing M, Zott B, Shi Y, Xiang X, Franzmeier N, Kleinberger G, Peters F, Ochs K, Focke C, Sacher C, Wind K, Schmidt C, Lindner S, Gildehaus FJ, Eckenweber F, Beyer L, von Ungern-Sternberg B, Bartenstein P, Baumann K, Dorostkar MM, Rominger A, Cumming P, Willem M, Adelsberger H, Herms J, Brendel M. Biechele G, et al. Among authors: zott b. Theranostics. 2021 Aug 19;11(18):8964-8976. doi: 10.7150/thno.64022. eCollection 2021. Theranostics. 2021. PMID: 34522221 Free PMC article.
Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition.
Blume T, Deussing M, Biechele G, Peters F, Zott B, Schmidt C, Franzmeier N, Wind K, Eckenweber F, Sacher C, Shi Y, Ochs K, Kleinberger G, Xiang X, Focke C, Lindner S, Gildehaus FJ, Beyer L, von Ungern-Sternberg B, Bartenstein P, Baumann K, Adelsberger H, Rominger A, Cumming P, Willem M, Dorostkar MM, Herms J, Brendel M. Blume T, et al. Among authors: zott b. Front Aging Neurosci. 2022 Mar 30;14:854031. doi: 10.3389/fnagi.2022.854031. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35431893 Free PMC article.
A vicious cycle of β amyloid-dependent neuronal hyperactivation.
Zott B, Simon MM, Hong W, Unger F, Chen-Engerer HJ, Frosch MP, Sakmann B, Walsh DM, Konnerth A. Zott B, et al. Science. 2019 Aug 9;365(6453):559-565. doi: 10.1126/science.aay0198. Science. 2019. PMID: 31395777 Free PMC article.
20 results