Fushman D - Search Results

1

Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention.

Nussinov R, Zhang M, Tsai CJ, Liao TJ, Fushman D, Jang H. Nussinov R, et al. Among authors: fushman d. Biophys Rev. 2018 Oct;10(5):1263-1282. doi: 10.1007/s12551-018-0461-0. Epub 2018 Sep 29. Biophys Rev. 2018. PMID: 30269291 Free PMC article. Review.

2

RASSF5: An MST activator and tumor suppressor in vivo but opposite in vitro.

Liao TJ, Tsai CJ, Jang H, Fushman D, Nussinov R. Liao TJ, et al. Among authors: fushman d. Curr Opin Struct Biol. 2016 Dec;41:217-224. doi: 10.1016/j.sbi.2016.09.001. Epub 2016 Sep 17. Curr Opin Struct Biol. 2016. PMID: 27643882 Review.

3

The dynamic mechanism of RASSF5 and MST kinase activation by Ras.

Liao TJ, Jang H, Tsai CJ, Fushman D, Nussinov R. Liao TJ, et al. Among authors: fushman d. Phys Chem Chem Phys. 2017 Mar 1;19(9):6470-6480. doi: 10.1039/c6cp08596b. Phys Chem Chem Phys. 2017. PMID: 28197608 Free PMC article.

4

Intrinsic protein disorder in oncogenic KRAS signaling.

Nussinov R, Jang H, Tsai CJ, Liao TJ, Li S, Fushman D, Zhang J. Nussinov R, et al. Among authors: fushman d. Cell Mol Life Sci. 2017 Sep;74(17):3245-3261. doi: 10.1007/s00018-017-2564-3. Epub 2017 Jun 8. Cell Mol Life Sci. 2017. PMID: 28597297 Free PMC article. Review.

5

Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles.

Liao TJ, Jang H, Fushman D, Nussinov R. Liao TJ, et al. Among authors: fushman d. Biophys J. 2018 Aug 21;115(4):629-641. doi: 10.1016/j.bpj.2018.07.016. Epub 2018 Jul 24. Biophys J. 2018. PMID: 30097175 Free PMC article.

6

High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1.

Liao TJ, Jang H, Nussinov R, Fushman D. Liao TJ, et al. Among authors: fushman d. J Am Chem Soc. 2020 Feb 19;142(7):3401-3411. doi: 10.1021/jacs.9b10710. Epub 2020 Feb 4. J Am Chem Soc. 2020. PMID: 31970984 Free PMC article.

7

SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations.

Liao TJ, Jang H, Fushman D, Nussinov R. Liao TJ, et al. Among authors: fushman d. J Chem Phys. 2020 Jul 28;153(4):045106. doi: 10.1063/5.0013926. J Chem Phys. 2020. PMID: 32752665 Free PMC article.

8

An efficient computational method for predicting rotational diffusion tensors of globular proteins using an ellipsoid representation.

Ryabov YE, Geraghty C, Varshney A, Fushman D. Ryabov YE, et al. Among authors: fushman d. J Am Chem Soc. 2006 Dec 6;128(48):15432-44. doi: 10.1021/ja062715t. J Am Chem Soc. 2006. PMID: 17132010

9

A model of interdomain mobility in a multidomain protein.

Ryabov YE, Fushman D. Ryabov YE, et al. Among authors: fushman d. J Am Chem Soc. 2007 Mar 21;129(11):3315-27. doi: 10.1021/ja067667r. Epub 2007 Feb 24. J Am Chem Soc. 2007. PMID: 17319663 Free PMC article.

10

Structural assembly of multidomain proteins and protein complexes guided by the overall rotational diffusion tensor.

Ryabov Y, Fushman D. Ryabov Y, et al. Among authors: fushman d. J Am Chem Soc. 2007 Jun 27;129(25):7894-902. doi: 10.1021/ja071185d. Epub 2007 Jun 6. J Am Chem Soc. 2007. PMID: 17550252 Free PMC article.

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