Läppchen T - Search Results

1

Optimized synthesis and indium complex formation with the bifunctional chelator NODIA-Me.

Weinmann C, Holland JP, Läppchen T, Scherer H, Maus S, Stemler T, Bohnenberger H, Ezziddin S, Kurz P, Bartholomä MD. Weinmann C, et al. Among authors: lappchen t. Org Biomol Chem. 2018 Oct 17;16(40):7503-7512. doi: 10.1039/c8ob01981a. Org Biomol Chem. 2018. PMID: 30276385

2

In vitro and in vivo evaluation of the bifunctional chelator NODIA-Me in combination with a prostate-specific membrane antigen targeting vector.

Läppchen T, Kiefer Y, Holland JP, Bartholomä MD. Läppchen T, et al. Nucl Med Biol. 2018 May;60:45-54. doi: 10.1016/j.nucmedbio.2018.03.002. Epub 2018 Mar 10. Nucl Med Biol. 2018. PMID: 29571066

3

Preparation and preclinical evaluation of a ⁶⁸Ga-labelled c(RGDfK) conjugate comprising the bifunctional chelator NODIA-Me.

Läppchen T, Holland JP, Kiefer Y, Bartholomä MD. Läppchen T, et al. EJNMMI Radiopharm Chem. 2018;3(1):6. doi: 10.1186/s41181-018-0043-2. Epub 2018 May 2. EJNMMI Radiopharm Chem. 2018. PMID: 29756024 Free PMC article.

4

Gallium Complexation, Stability, and Bioconjugation of 1,4,7-Triazacyclononane Derived Chelators with Azaheterocyclic Arms.

Schmidtke A, Läppchen T, Weinmann C, Bier-Schorr L, Keller M, Kiefer Y, Holland JP, Bartholomä MD. Schmidtke A, et al. Among authors: lappchen t. Inorg Chem. 2017 Aug 7;56(15):9097-9110. doi: 10.1021/acs.inorgchem.7b01129. Epub 2017 Jul 25. Inorg Chem. 2017. PMID: 28742337

5

DOTA-tetrazine probes with modified linkers for tumor pretargeting.

Läppchen T, Rossin R, van Mourik TR, Gruntz G, Hoeben FJM, Versteegen RM, Janssen HM, Lub J, Robillard MS. Läppchen T, et al. Nucl Med Biol. 2017 Dec;55:19-26. doi: 10.1016/j.nucmedbio.2017.09.001. Epub 2017 Sep 14. Nucl Med Biol. 2017. PMID: 29028502

6

Combination of Forced Diuresis with Additional Late Imaging in ⁶⁸Ga-PSMA-11 PET/CT: Effects on Lesion Visibility and Radiotracer Uptake.

Alberts I, Niklas-Hünermund J, Sachpekidis C, Zacho HD, Mingels C, Dijkstra L, Bohn KP, Läppchen T, Gourni E, Rominger A, Afshar-Oromieh A. Alberts I, et al. Among authors: lappchen t. J Nucl Med. 2021 Sep 1;62(9):1252-1257. doi: 10.2967/jnumed.120.257741. Epub 2021 Feb 5. J Nucl Med. 2021. PMID: 33547214 Free article.

7

Diels-Alder reaction for tumor pretargeting: in vivo chemistry can boost tumor radiation dose compared with directly labeled antibody.

Rossin R, Läppchen T, van den Bosch SM, Laforest R, Robillard MS. Rossin R, et al. Among authors: lappchen t. J Nucl Med. 2013 Nov;54(11):1989-95. doi: 10.2967/jnumed.113.123745. Epub 2013 Oct 3. J Nucl Med. 2013. PMID: 24092936 Free article.

8

Trans-cyclooctene tag with improved properties for tumor pretargeting with the diels-alder reaction.

Rossin R, van Duijnhoven SM, Läppchen T, van den Bosch SM, Robillard MS. Rossin R, et al. Among authors: lappchen t. Mol Pharm. 2014 Sep 2;11(9):3090-6. doi: 10.1021/mp500275a. Epub 2014 Aug 13. Mol Pharm. 2014. PMID: 25077373

9

Novel analogs of antitumor agent calixarene 0118: Synthesis, cytotoxicity, click labeling with 2-[(18)F]fluoroethylazide, and in vivo evaluation.

Läppchen T, Dings RP, Rossin R, Simon JF, Visser TJ, Bakker M, Walhe P, van Mourik T, Donato K, van Beijnum JR, Griffioen AW, Lub J, Robillard MS, Mayo KH, Grüll H. Läppchen T, et al. Eur J Med Chem. 2015 Jan 7;89:279-95. doi: 10.1016/j.ejmech.2014.10.048. Epub 2014 Oct 18. Eur J Med Chem. 2015. PMID: 25462244

10

Evaluation of 111In-labeled Anginex as Potential SPECT Tracer for Imaging of Tumor Angiogenesis.

Van Mourik TR, Läppchen T, Rossin R, Van Beijnum JR, Macdonald JR, Mayo KH, Griffioen AW, Nicolay K, Grüll H. Van Mourik TR, et al. Among authors: lappchen t. Anticancer Res. 2015 Nov;35(11):5945-54. Anticancer Res. 2015. PMID: 26504018

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