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Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents.
Bajor M, Zych AO, Graczyk-Jarzynka A, Muchowicz A, Firczuk M, Trzeciak L, Gaj P, Domagala A, Siernicka M, Zagozdzon A, Siedlecki P, Kniotek M, O'Leary PC, Golab J, Zagozdzon R. Bajor M, et al. Among authors: gaj p. Br J Cancer. 2018 Oct;119(7):873-884. doi: 10.1038/s41416-018-0263-y. Epub 2018 Oct 5. Br J Cancer. 2018. PMID: 30287919 Free PMC article.
Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer.
O'Leary PC, Terrile M, Bajor M, Gaj P, Hennessy BT, Mills GB, Zagozdzon A, O'Connor DP, Brennan DJ, Connor K, Li J, Gonzalez-Angulo AM, Sun HD, Pu JX, Pontén F, Uhlén M, Jirström K, Nowis DA, Crown JP, Zagozdzon R, Gallagher WM. O'Leary PC, et al. Among authors: gaj p. Breast Cancer Res. 2014 Jul 10;16(4):R79. doi: 10.1186/bcr3691. Breast Cancer Res. 2014. PMID: 25011585 Free PMC article.
Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma.
Trzeciecka A, Klossowski S, Bajor M, Zagozdzon R, Gaj P, Muchowicz A, Malinowska A, Czerwoniec A, Barankiewicz J, Domagala A, Chlebowska J, Prochorec-Sobieszek M, Winiarska M, Ostaszewski R, Gwizdalska I, Golab J, Nowis D, Firczuk M. Trzeciecka A, et al. Among authors: gaj p. Oncotarget. 2016 Jan 12;7(2):1717-31. doi: 10.18632/oncotarget.6435. Oncotarget. 2016. PMID: 26636537 Free PMC article.
Inhibition of protein disulfide isomerase induces differentiation of acute myeloid leukemia cells.
Chlebowska-Tuz J, Sokolowska O, Gaj P, Lazniewski M, Firczuk M, Borowiec K, Sas-Nowosielska H, Bajor M, Malinowska A, Muchowicz A, Ramji K, Stawinski P, Sobczak M, Pilch Z, Rodziewicz-Lurzynska A, Zajac M, Giannopoulos K, Juszczynski P, Basak GW, Plewczynski D, Ploski R, Golab J, Nowis D. Chlebowska-Tuz J, et al. Among authors: gaj p. Haematologica. 2018 Nov;103(11):1843-1852. doi: 10.3324/haematol.2018.190231. Epub 2018 Jul 12. Haematologica. 2018. PMID: 30002127 Free PMC article.
Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma.
Czystowska-Kuzmicz M, Sosnowska A, Nowis D, Ramji K, Szajnik M, Chlebowska-Tuz J, Wolinska E, Gaj P, Grazul M, Pilch Z, Zerrouqi A, Graczyk-Jarzynka A, Soroczynska K, Cierniak S, Koktysz R, Elishaev E, Gruca S, Stefanowicz A, Blaszczyk R, Borek B, Gzik A, Whiteside T, Golab J. Czystowska-Kuzmicz M, et al. Among authors: gaj p. Nat Commun. 2019 Jul 5;10(1):3000. doi: 10.1038/s41467-019-10979-3. Nat Commun. 2019. PMID: 31278254 Free PMC article.
32 results