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Development of an LC-ESI(-)-MS/MS method for the simultaneous quantification of 35 isoprostanes and isofurans derived from the major n3- and n6-PUFAs.
Anal Chim Acta. 2018 Dec 11;1037:63-74. doi: 10.1016/j.aca.2017.11.002. Epub 2017 Nov 14.
Anal Chim Acta. 2018.
PMID: 30292316
Formation of trans-epoxy fatty acids correlates with formation of isoprostanes and could serve as biomarker of oxidative stress.
Rund KM, Heylmann D, Seiwert N, Wecklein S, Oger C, Galano JM, Durand T, Chen R, Gueler F, Fahrer J, Bornhorst J, Schebb NH.
Rund KM, et al. Among authors: wecklein s.
Prostaglandins Other Lipid Mediat. 2019 Oct;144:106334. doi: 10.1016/j.prostaglandins.2019.04.004. Epub 2019 Apr 19.
Prostaglandins Other Lipid Mediat. 2019.
PMID: 31009766
Review.
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Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron.
Seiwert N, Wecklein S, Demuth P, Hasselwander S, Kemper TA, Schwerdtle T, Brunner T, Fahrer J.
Seiwert N, et al. Among authors: wecklein s.
Cell Death Dis. 2020 Sep 23;11(9):787. doi: 10.1038/s41419-020-02950-8.
Cell Death Dis. 2020.
PMID: 32968051
Free PMC article.
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Artemisinin Derivatives Target Topoisomerase 1 and Cause DNA Damage in Silico and in Vitro.
Kadioglu O, Chan A, Cong Ling Qiu A, Wong VKW, Colligs V, Wecklein S, Freund-Henni Rached H, Efferth T, Hsiao WW.
Kadioglu O, et al. Among authors: wecklein s.
Front Pharmacol. 2017 Oct 9;8:711. doi: 10.3389/fphar.2017.00711. eCollection 2017.
Front Pharmacol. 2017.
PMID: 29062278
Free PMC article.
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