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A combination of irinotecan/cisplatinum and irinotecan/temozolomide or tumor-targeting Salmonella typhimurium A1-R arrest doxorubicin- and temozolomide-resistant myxofibrosarcoma in a PDOX mouse model.
Kiyuna T, Tome Y, Murakami T, Miyake K, Igarashi K, Kawaguchi K, Oshiro H, Higuchi T, Miyake M, Sugisawa N, Zhang Z, Razmjooei S, Wangsiricharoen S, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Eckardt MA, Singh AS, Chawla S, Kanaya F, Eilber FC, Singh SR, Zhao M, Hoffman RM. Kiyuna T, et al. Among authors: miyake k, miyake m. Biochem Biophys Res Commun. 2018 Nov 2;505(3):733-739. doi: 10.1016/j.bbrc.2018.09.106. Epub 2018 Oct 3. Biochem Biophys Res Commun. 2018. PMID: 30292411
Cervical Cancer Patient-Derived Orthotopic Xenograft (PDOX) Is Sensitive to Cisplatinum and Resistant to Nab-paclitaxel.
Murakami T, Murata T, Kawaguchi K, Kiyuna T, Igarashi K, Hwang HK, Hiroshima Y, Hozumi C, Komatsu S, Kikuchi T, Lwin TM, Delong JC, Miyake K, Zhang Y, Tanaka K, Bouvet M, Endo I, Hoffman RM. Murakami T, et al. Among authors: miyake k. Anticancer Res. 2017 Jan;37(1):61-65. doi: 10.21873/anticanres.11289. Anticancer Res. 2017. PMID: 28011474 Free PMC article.
High Efficacy of Pazopanib on an Undifferentiated Spindle-Cell Sarcoma Resistant to First-Line Therapy Is Identified With a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model.
Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Singh AS, Nelson SD, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: miyake k. J Cell Biochem. 2017 Sep;118(9):2739-2743. doi: 10.1002/jcb.25923. Epub 2017 Apr 25. J Cell Biochem. 2017. PMID: 28176365
The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago.
Murakami T, Kiyuna T, Kawaguchi K, Igarashi K, Singh AS, Hiroshima Y, Zhang Y, Zhao M, Miyake K, Nelson SD, Dry SM, Li Y, DeLong JC, Lwin TM, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. Murakami T, et al. Among authors: miyake k. Cell Cycle. 2017 Jun 3;16(11):1046-1052. doi: 10.1080/15384101.2017.1304340. Epub 2017 Mar 15. Cell Cycle. 2017. PMID: 28296559 Free PMC article.
Analysis of Stroma Labeling During Multiple Passage of a Sarcoma Imageable Patient-Derived Orthotopic Xenograft (iPDOX) in Red Fluorescent Protein Transgenic Nude Mice.
Kiyuna T, Murakami T, Tome Y, Kawaguchi K, Igarashi K, Miyake K, Kanaya F, Singh A, Eilber FC, Hoffman RM. Kiyuna T, et al. Among authors: miyake k. J Cell Biochem. 2017 Oct;118(10):3367-3371. doi: 10.1002/jcb.25991. Epub 2017 May 15. J Cell Biochem. 2017. PMID: 28300287 Free PMC article.
Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
Murakami T, Li S, Han Q, Tan Y, Kiyuna T, Igarashi K, Kawaguchi K, Hwang HK, Miyake K, Singh AS, Nelson SD, Dry SM, Li Y, Hiroshima Y, Lwin TM, DeLong JC, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. Murakami T, et al. Among authors: miyake k. Oncotarget. 2017 May 30;8(22):35630-35638. doi: 10.18632/oncotarget.15823. Oncotarget. 2017. PMID: 28404944 Free PMC article.
Color-coded intravital imaging demonstrates a transforming growth factor-β (TGF-β) antagonist selectively targets stromal cells in a human pancreatic-cancer orthotopic mouse model.
Murakami T, Hiroshima Y, Miyake K, Hwang HK, Kiyuna T, DeLong JC, Lwin TM, Matsuyama R, Mori R, Kumamoto T, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. Murakami T, et al. Among authors: miyake k. Cell Cycle. 2017 May 19;16(10):1008-1014. doi: 10.1080/15384101.2017.1315489. Epub 2017 Apr 25. Cell Cycle. 2017. PMID: 28441080 Free PMC article.
Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model.
Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Nelson SD, Dry SM, Li Y, Yanagawa J, Russell TA, Singh AS, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: miyake k. Cell Cycle. 2017 Jun 18;16(12):1164-1170. doi: 10.1080/15384101.2017.1317417. Epub 2017 May 11. Cell Cycle. 2017. PMID: 28494180 Free PMC article.
Neoadjuvant chemoradiotherapy of pancreatic cancer induces a favorable immunogenic tumor microenvironment associated with increased major histocompatibility complex class I-related chain A/B expression.
Murakami T, Homma Y, Matsuyama R, Mori R, Miyake K, Tanaka Y, Den K, Nagashima Y, Nakazawa M, Hiroshima Y, Ueda M, Tanaka K, Hoffman RM, Bouvet M, Endo I. Murakami T, et al. Among authors: miyake k. J Surg Oncol. 2017 Sep;116(3):416-426. doi: 10.1002/jso.24681. Epub 2017 Jun 12. J Surg Oncol. 2017. PMID: 28608409
Tumor-Targeting Salmonella typhimurium A1-R Promotes Tumoricidal CD8+ T Cell Tumor Infiltration and Arrests Growth and Metastasis in a Syngeneic Pancreatic-Cancer Orthotopic Mouse Model.
Murakami T, Hiroshima Y, Zhang Y, Zhao M, Kiyuna T, Hwang HK, Miyake K, Homma Y, Mori R, Matsuyama R, Chishima T, Ichikawa Y, Tanaka K, Bouvet M, Endo I, Hoffman RM. Murakami T, et al. Among authors: miyake k. J Cell Biochem. 2018 Jan;119(1):634-639. doi: 10.1002/jcb.26224. Epub 2017 Aug 11. J Cell Biochem. 2018. PMID: 28628234
2,082 results