Alteen MG - Search Results

1

Direct One-Step Fluorescent Labeling of O-GlcNAc-Modified Proteins in Live Cells Using Metabolic Intermediates.

Tan HY, Eskandari R, Shen D, Zhu Y, Liu TW, Willems LI, Alteen MG, Madden Z, Vocadlo DJ. Tan HY, et al. Among authors: alteen mg. J Am Chem Soc. 2018 Nov 14;140(45):15300-15308. doi: 10.1021/jacs.8b08260. Epub 2018 Oct 22. J Am Chem Soc. 2018. PMID: 30296064 Free article.

2

Mechanism of Human Nucleocytoplasmic Hexosaminidase D.

Alteen MG, Oehler V, Nemčovičová I, Wilson IB, Vocadlo DJ, Gloster TM. Alteen MG, et al. Biochemistry. 2016 May 17;55(19):2735-47. doi: 10.1021/acs.biochem.5b01285. Epub 2016 May 5. Biochemistry. 2016. PMID: 27149221 Free PMC article.

3

Catalytic Promiscuity of O-GlcNAc Transferase Enables Unexpected Metabolic Engineering of Cytoplasmic Proteins with 2-Azido-2-deoxy-glucose.

Shen DL, Liu TW, Zandberg W, Clark T, Eskandari R, Alteen MG, Tan HY, Zhu Y, Cecioni S, Vocadlo D. Shen DL, et al. Among authors: alteen mg. ACS Chem Biol. 2017 Jan 20;12(1):206-213. doi: 10.1021/acschembio.6b00876. Epub 2016 Dec 9. ACS Chem Biol. 2017. PMID: 27935279

4

A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High-Throughput Screening: Application to O-GlcNAc Transferase.

Alteen MG, Gros C, Meek RW, Cardoso DA, Busmann JA, Sangouard G, Deen MC, Tan HY, Shen DL, Russell CC, Davies GJ, Robinson PJ, McCluskey A, Vocadlo DJ. Alteen MG, et al. Angew Chem Int Ed Engl. 2020 Jun 8;59(24):9601-9609. doi: 10.1002/anie.202000621. Epub 2020 Apr 2. Angew Chem Int Ed Engl. 2020. PMID: 32092778

5

Precision Mapping of O-Linked N-Acetylglucosamine Sites in Proteins Using Ultraviolet Photodissociation Mass Spectrometry.

Escobar EE, King DT, Serrano-Negrón JE, Alteen MG, Vocadlo DJ, Brodbelt JS. Escobar EE, et al. Among authors: alteen mg. J Am Chem Soc. 2020 Jul 1;142(26):11569-11577. doi: 10.1021/jacs.0c04710. Epub 2020 Jun 19. J Am Chem Soc. 2020. PMID: 32510947 Free PMC article.

6

Monitoring and modulating O-GlcNAcylation: assays and inhibitors of O-GlcNAc processing enzymes.

Alteen MG, Tan HY, Vocadlo DJ. Alteen MG, et al. Curr Opin Struct Biol. 2021 Jun;68:157-165. doi: 10.1016/j.sbi.2020.12.008. Epub 2021 Jan 31. Curr Opin Struct Biol. 2021. PMID: 33535148 Review.

7

Cryo-EM structure provides insights into the dimer arrangement of the O-linked β-N-acetylglucosamine transferase OGT.

Meek RW, Blaza JN, Busmann JA, Alteen MG, Vocadlo DJ, Davies GJ. Meek RW, et al. Among authors: alteen mg. Nat Commun. 2021 Nov 11;12(1):6508. doi: 10.1038/s41467-021-26796-6. Nat Commun. 2021. PMID: 34764280 Free PMC article.

8

Discovery of a New Drug-like Series of OGT Inhibitors by Virtual Screening.

Loi EM, Tomašič T, Balsollier C, van Eekelen K, Weiss M, Gobec M, Alteen MG, Vocadlo DJ, Pieters RJ, Anderluh M. Loi EM, et al. Among authors: alteen mg. Molecules. 2022 Mar 19;27(6):1996. doi: 10.3390/molecules27061996. Molecules. 2022. PMID: 35335358 Free PMC article.

9

Potent De Novo Macrocyclic Peptides That Inhibit O-GlcNAc Transferase through an Allosteric Mechanism.

Alteen MG, Peacock H, Meek RW, Busmann JA, Zhu S, Davies GJ, Suga H, Vocadlo DJ. Alteen MG, et al. Angew Chem Int Ed Engl. 2023 Jan 26;62(5):e202215671. doi: 10.1002/anie.202215671. Epub 2022 Dec 27. Angew Chem Int Ed Engl. 2023. PMID: 36460613 Free article.

10

HBP/O-GlcNAcylation Metabolic Axis Regulates Bone Resorption Outcome.

Taira TM, Ramos-Junior ES, Melo PH, Costa-Silva CC, Alteen MG, Vocadlo DJ, Dias WB, Cunha FQ, Alves-Filho JC, Søe K, Fukada SY. Taira TM, et al. Among authors: alteen mg. J Dent Res. 2023 Apr;102(4):440-449. doi: 10.1177/00220345221141043. Epub 2023 Feb 7. J Dent Res. 2023. PMID: 36749069

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