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Ultrasmall targeted nanoparticles with engineered antibody fragments for imaging detection of HER2-overexpressing breast cancer.
Chen F, Ma K, Madajewski B, Zhuang L, Zhang L, Rickert K, Marelli M, Yoo B, Turker MZ, Overholtzer M, Quinn TP, Gonen M, Zanzonico P, Tuesca A, Bowen MA, Norton L, Subramony JA, Wiesner U, Bradbury MS. Chen F, et al. Nat Commun. 2018 Oct 8;9(1):4141. doi: 10.1038/s41467-018-06271-5. Nat Commun. 2018. PMID: 30297810 Free PMC article.
Melanocortin-1 Receptor-Targeting Ultrasmall Silica Nanoparticles for Dual-Modality Human Melanoma Imaging.
Chen F, Zhang X, Ma K, Madajewski B, Benezra M, Zhang L, Phillips E, Turker MZ, Gallazzi F, Penate-Medina O, Overholtzer M, Pauliah M, Gonen M, Zanzonico P, Wiesner U, Bradbury MS, Quinn TP. Chen F, et al. ACS Appl Mater Interfaces. 2018 Feb 7;10(5):4379-4393. doi: 10.1021/acsami.7b14362. Epub 2018 Jan 24. ACS Appl Mater Interfaces. 2018. PMID: 29058865 Free PMC article.
Ultrasmall Renally Clearable Silica Nanoparticles Target Prostate Cancer.
Chen F, Ma K, Zhang L, Madajewski B, Turker MZ, Gallazzi F, Cruickshank K, Zhang X, Jenjitranant P, Touijer KA, Quinn TP, Zanzonico P, Wiesner U, Bradbury MS. Chen F, et al. ACS Appl Mater Interfaces. 2019 Nov 27;11(47):43879-43887. doi: 10.1021/acsami.9b15195. Epub 2019 Nov 13. ACS Appl Mater Interfaces. 2019. PMID: 31675204 Free PMC article.
Molecular phenotyping and image-guided surgical treatment of melanoma using spectrally distinct ultrasmall core-shell silica nanoparticles.
Chen F, Madajewski B, Ma K, Karassawa Zanoni D, Stambuk H, Turker MZ, Monette S, Zhang L, Yoo B, Chen P, Meester RJC, de Jonge S, Montero P, Phillips E, Quinn TP, Gönen M, Sequeira S, de Stanchina E, Zanzonico P, Wiesner U, Patel SG, Bradbury MS. Chen F, et al. Among authors: chen p. Sci Adv. 2019 Dec 4;5(12):eaax5208. doi: 10.1126/sciadv.aax5208. eCollection 2019 Dec. Sci Adv. 2019. PMID: 31840066 Free PMC article.
Molecular Engineering of Ultrasmall Silica Nanoparticle-Drug Conjugates as Lung Cancer Therapeutics.
Madajewski B, Chen F, Yoo B, Turker MZ, Ma K, Zhang L, Chen PM, Juthani R, Aragon-Sanabria V, Gonen M, Rudin CM, Wiesner U, Bradbury MS, Brennan C. Madajewski B, et al. Among authors: chen f, chen pm. Clin Cancer Res. 2020 Oct 15;26(20):5424-5437. doi: 10.1158/1078-0432.CCR-20-0851. Epub 2020 Jul 28. Clin Cancer Res. 2020. PMID: 32723835 Free PMC article.
Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model.
Juthani R, Madajewski B, Yoo B, Zhang L, Chen PM, Chen F, Turker MZ, Ma K, Overholtzer M, Longo VA, Carlin S, Aragon-Sanabria V, Huse J, Gonen M, Zanzonico P, Rudin CM, Wiesner U, Bradbury MS, Brennan CW. Juthani R, et al. Among authors: chen f, chen pm. Clin Cancer Res. 2020 Jan 1;26(1):147-158. doi: 10.1158/1078-0432.CCR-19-1834. Epub 2019 Sep 12. Clin Cancer Res. 2020. PMID: 31515460 Free PMC article.
A Genomic Profile of Local Immunity in the Melanoma Microenvironment Following Treatment with α Particle-Emitting Ultrasmall Silica Nanoparticles.
Urbanska AM, Khanin R, Alidori S, Wong S, Mello BP, Almeida BA, Chen F, Ma K, Turker MZ, Korontsvit T, Scheinberg DA, Zanzonico PB, Wiesner U, Bradbury MS, Quinn TP, McDevitt MR. Urbanska AM, et al. Among authors: chen f. Cancer Biother Radiopharm. 2020 Aug;35(6):459-473. doi: 10.1089/cbr.2019.3150. Epub 2020 Feb 3. Cancer Biother Radiopharm. 2020. PMID: 32013538 Free PMC article.
Ultrasmall Nanoparticle Delivery of Doxorubicin Improves Therapeutic Index for High-Grade Glioma.
Aragon-Sanabria V, Aditya A, Zhang L, Chen F, Yoo B, Cao T, Madajewski B, Lee R, Turker MZ, Ma K, Monette S, Chen P, Wu J, Ruan S, Overholtzer M, Zanzonico P, Rudin CM, Brennan C, Wiesner U, Bradbury MS. Aragon-Sanabria V, et al. Among authors: chen p, chen f. Clin Cancer Res. 2022 Jul 1;28(13):2938-2952. doi: 10.1158/1078-0432.CCR-21-4053. Clin Cancer Res. 2022. PMID: 35499557 Free PMC article.
Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth.
Kim SE, Zhang L, Ma K, Riegman M, Chen F, Ingold I, Conrad M, Turker MZ, Gao M, Jiang X, Monette S, Pauliah M, Gonen M, Zanzonico P, Quinn T, Wiesner U, Bradbury MS, Overholtzer M. Kim SE, et al. Among authors: chen f. Nat Nanotechnol. 2016 Nov;11(11):977-985. doi: 10.1038/nnano.2016.164. Epub 2016 Sep 26. Nat Nanotechnol. 2016. PMID: 27668796 Free PMC article.
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