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Molecular mechanism of activation of the immunoregulatory amidase NAAA.
Gorelik A, Gebai A, Illes K, Piomelli D, Nagar B. Gorelik A, et al. Among authors: illes k. Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10032-E10040. doi: 10.1073/pnas.1811759115. Epub 2018 Oct 9. Proc Natl Acad Sci U S A. 2018. PMID: 30301806 Free PMC article.
Crystal structure of mammalian acid sphingomyelinase.
Gorelik A, Illes K, Heinz LX, Superti-Furga G, Nagar B. Gorelik A, et al. Among authors: illes k. Nat Commun. 2016 Jul 20;7:12196. doi: 10.1038/ncomms12196. Nat Commun. 2016. PMID: 27435900 Free PMC article.
Crystal structure of the mammalian lipopolysaccharide detoxifier.
Gorelik A, Illes K, Nagar B. Gorelik A, et al. Among authors: illes k. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E896-E905. doi: 10.1073/pnas.1719834115. Epub 2018 Jan 17. Proc Natl Acad Sci U S A. 2018. PMID: 29343645 Free PMC article.
Structural basis for the activation of acid ceramidase.
Gebai A, Gorelik A, Li Z, Illes K, Nagar B. Gebai A, et al. Among authors: illes k. Nat Commun. 2018 Apr 24;9(1):1621. doi: 10.1038/s41467-018-03844-2. Nat Commun. 2018. PMID: 29692406 Free PMC article.
Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur.
Dementiev A, Joachimiak A, Nguyen H, Gorelik A, Illes K, Shabani S, Gelsomino M, Ahn EE, Nagar B, Doan N. Dementiev A, et al. Among authors: illes k. J Med Chem. 2019 Jan 24;62(2):987-992. doi: 10.1021/acs.jmedchem.8b01723. Epub 2018 Dec 19. J Med Chem. 2019. PMID: 30525581 Free PMC article.
42 results