Calabrese DR - Search Results

1

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.

Calabrese DR, Chen X, Leon EC, Gaikwad SM, Phyo Z, Hewitt WM, Alden S, Hilimire TA, He F, Michalowski AM, Simmons JK, Saunders LB, Zhang S, Connors D, Walters KJ, Mock BA, Schneekloth JS Jr. Calabrese DR, et al. Nat Commun. 2018 Oct 12;9(1):4229. doi: 10.1038/s41467-018-06315-w. Nat Commun. 2018. PMID: 30315240 Free PMC article.

2

Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression.

Felsenstein KM, Saunders LB, Simmons JK, Leon E, Calabrese DR, Zhang S, Michalowski A, Gareiss P, Mock BA, Schneekloth JS Jr. Felsenstein KM, et al. Among authors: calabrese dr. ACS Chem Biol. 2016 Jan 15;11(1):139-48. doi: 10.1021/acschembio.5b00577. Epub 2015 Nov 6. ACS Chem Biol. 2016. PMID: 26462961 Free PMC article.

3

Characterization of clinically used oral antiseptics as quadruplex-binding ligands.

Calabrese DR, Zlotkowski K, Alden S, Hewitt WM, Connelly CM, Wilson RM, Gaikwad S, Chen L, Guha R, Thomas CJ, Mock BA, Schneekloth JS Jr. Calabrese DR, et al. Nucleic Acids Res. 2018 Apr 6;46(6):2722-2732. doi: 10.1093/nar/gky084. Nucleic Acids Res. 2018. PMID: 29481610 Free PMC article.

4

Evidence for ligandable sites in structured RNA throughout the Protein Data Bank.

Hewitt WM, Calabrese DR, Schneekloth JS Jr. Hewitt WM, et al. Among authors: calabrese dr. Bioorg Med Chem. 2019 Jun 1;27(11):2253-2260. doi: 10.1016/j.bmc.2019.04.010. Epub 2019 Apr 6. Bioorg Med Chem. 2019. PMID: 30982658 Free PMC article.

5

Ligand-observed NMR techniques to probe RNA-small molecule interactions.

Calabrese DR, Connelly CM, Schneekloth JS Jr. Calabrese DR, et al. Methods Enzymol. 2019;623:131-149. doi: 10.1016/bs.mie.2019.05.030. Epub 2019 Jun 6. Methods Enzymol. 2019. PMID: 31239044 Free PMC article.

6

A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma.

Gaikwad SM, Phyo Z, Arteaga AQ, Gorjifard S, Calabrese DR, Connors D, Huang J, Michalowski AM, Zhang S, Liu ZG, Schneekloth JS Jr, Mock BA. Gaikwad SM, et al. Among authors: calabrese dr. Cancers (Basel). 2020 Oct 13;12(10):2952. doi: 10.3390/cancers12102952. Cancers (Basel). 2020. PMID: 33066043 Free PMC article.

7

Targeting a noncanonical, hairpin-containing G-quadruplex structure from the MYCN gene.

Yang M, Carter S, Parmar S, Bume DD, Calabrese DR, Liang X, Yazdani K, Xu M, Liu Z, Thiele CJ, Schneekloth JS. Yang M, et al. Among authors: calabrese dr. Nucleic Acids Res. 2021 Aug 20;49(14):7856-7869. doi: 10.1093/nar/gkab594. Nucleic Acids Res. 2021. PMID: 34289065 Free PMC article.

8

Machine Learning Informs RNA-Binding Chemical Space.

Yazdani K, Jordan D, Yang M, Fullenkamp CR, Calabrese DR, Boer R, Hilimire T, Allen TEH, Khan RT, Schneekloth JS Jr. Yazdani K, et al. Among authors: calabrese dr. Angew Chem Int Ed Engl. 2023 Mar 6;62(11):e202211358. doi: 10.1002/anie.202211358. Epub 2023 Feb 6. Angew Chem Int Ed Engl. 2023. PMID: 36584293 Free PMC article.

9

Investigating the NRAS 5' UTR as a target for small molecules.

Balaratnam S, Torrey ZR, Calabrese DR, Banco MT, Yazdani K, Liang X, Fullenkamp CR, Seshadri S, Holewinski RJ, Andresson T, Ferré-D'Amaré AR, Incarnato D, Schneekloth JS Jr. Balaratnam S, et al. Among authors: calabrese dr. Cell Chem Biol. 2023 Jun 15;30(6):643-657.e8. doi: 10.1016/j.chembiol.2023.05.004. Epub 2023 May 30. Cell Chem Biol. 2023. PMID: 37257453 Free PMC article.

10

Improving the odds: Reducing diagnostic uncertainty with bronchoalveolar lavage cytokine profiling.

Calabrese DR, Leard LE. Calabrese DR, et al. J Heart Lung Transplant. 2024 Dec 11:S1053-2498(24)02011-4. doi: 10.1016/j.healun.2024.12.002. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 39672288 No abstract available.

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