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In utero priming of highly functional effector T cell responses to human malaria.
Odorizzi PM, Jagannathan P, McIntyre TI, Budker R, Prahl M, Auma A, Burt TD, Nankya F, Nalubega M, Sikyomu E, Musinguzi K, Naluwu K, Kakuru A, Dorsey G, Kamya MR, Feeney ME. Odorizzi PM, et al. Among authors: auma a. Sci Transl Med. 2018 Oct 17;10(463):eaat6176. doi: 10.1126/scitranslmed.aat6176. Sci Transl Med. 2018. PMID: 30333241 Free PMC article.
IFNγ/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children.
Jagannathan P, Eccles-James I, Bowen K, Nankya F, Auma A, Wamala S, Ebusu C, Muhindo MK, Arinaitwe E, Briggs J, Greenhouse B, Tappero JW, Kamya MR, Dorsey G, Feeney ME. Jagannathan P, et al. Among authors: auma a. PLoS Pathog. 2014 Jan;10(1):e1003864. doi: 10.1371/journal.ppat.1003864. Epub 2014 Jan 9. PLoS Pathog. 2014. PMID: 24415936 Free PMC article. Clinical Trial.
Effective Antimalarial Chemoprevention in Childhood Enhances the Quality of CD4+ T Cells and Limits Their Production of Immunoregulatory Interleukin 10.
Jagannathan P, Bowen K, Nankya F, McIntyre TI, Auma A, Wamala S, Sikyomu E, Naluwu K, Nalubega M, Boyle MJ, Farrington LA, Bigira V, Kapisi J, Aweeka F, Greenhouse B, Kamya M, Dorsey G, Feeney ME. Jagannathan P, et al. Among authors: auma a. J Infect Dis. 2016 Jul 15;214(2):329-38. doi: 10.1093/infdis/jiw147. Epub 2016 Apr 10. J Infect Dis. 2016. PMID: 27067196 Free PMC article. Clinical Trial.
Timing of in utero malaria exposure influences fetal CD4 T cell regulatory versus effector differentiation.
Prahl M, Jagannathan P, McIntyre TI, Auma A, Farrington L, Wamala S, Nalubega M, Musinguzi K, Naluwu K, Sikyoma E, Budker R, Vance H, Odorizzi P, Nayebare P, Ategeka J, Kakuru A, Havlir DV, Kamya MR, Dorsey G, Feeney ME. Prahl M, et al. Among authors: auma a. Malar J. 2016 Oct 7;15(1):497. doi: 10.1186/s12936-016-1545-6. Malar J. 2016. PMID: 27717402 Free PMC article.
Sex Disparity in Cord Blood FoxP3+ CD4 T Regulatory Cells in Infants Exposed to Malaria In Utero.
Prahl M, Jagannathan P, McIntyre TI, Auma A, Wamala S, Nalubega M, Musinguzi K, Naluwu K, Sikyoma E, Budker R, Odorizzi P, Kakuru A, Havlir DV, Kamya MR, Dorsey G, Feeney ME. Prahl M, et al. Among authors: auma a. Open Forum Infect Dis. 2017 Feb 11;4(1):ofx022. doi: 10.1093/ofid/ofx022. eCollection 2017 Winter. Open Forum Infect Dis. 2017. PMID: 28480292 Free PMC article.
Exposure to pesticides in utero impacts the fetal immune system and response to vaccination in infancy.
Prahl M, Odorizzi P, Gingrich D, Muhindo M, McIntyre T, Budker R, Jagannathan P, Farrington L, Nalubega M, Nankya F, Sikyomu E, Musinguzi K, Naluwu K, Auma A, Kakuru A, Kamya MR, Dorsey G, Aweeka F, Feeney ME. Prahl M, et al. Among authors: auma a. Nat Commun. 2021 Jan 8;12(1):132. doi: 10.1038/s41467-020-20475-8. Nat Commun. 2021. PMID: 33420104 Free PMC article.
Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria.
Boyle MJ, Jagannathan P, Farrington LA, Eccles-James I, Wamala S, McIntyre TI, Vance HM, Bowen K, Nankya F, Auma A, Nalubega M, Sikyomu E, Naluwu K, Rek J, Katureebe A, Bigira V, Kapisi J, Tappero J, Muhindo MK, Greenhouse B, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME. Boyle MJ, et al. Among authors: auma a. PLoS Pathog. 2015 Jul 16;11(7):e1005041. doi: 10.1371/journal.ppat.1005041. eCollection 2015 Jul. PLoS Pathog. 2015. PMID: 26182204 Free PMC article.
Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood.
Farrington LA, Jagannathan P, McIntyre TI, Vance HM, Bowen K, Boyle MJ, Nankya F, Wamala S, Auma A, Nalubega M, Sikyomu E, Naluwu K, Bigira V, Kapisi J, Dorsey G, Kamya MR, Feeney ME. Farrington LA, et al. Among authors: auma a. J Infect Dis. 2016 May 1;213(9):1483-90. doi: 10.1093/infdis/jiv600. Epub 2015 Dec 13. J Infect Dis. 2016. PMID: 26667315 Free PMC article. Clinical Trial.
T-cell Activation Is Correlated With Monocyte Activation in HCV/HIV Coinfection and Declines During HCV Direct-Acting Antiviral Therapy.
Auma AWN, Shive C, Damjanovska S, Kowal C, Cohen DE, Bhattacharya D, Alston-Smith B, Osborne M, Kalayjian R, Balagopal A, Sulkowski M, Wyles D, Anthony DD. Auma AWN, et al. Open Forum Infect Dis. 2021 Feb 18;8(4):ofab079. doi: 10.1093/ofid/ofab079. eCollection 2021 Apr. Open Forum Infect Dis. 2021. PMID: 33880389 Free PMC article.
31 results