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706 results

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Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis.
Riva B, Griglio A, Serafini M, Cordero-Sanchez C, Aprile S, Di Paola R, Gugliandolo E, Alansary D, Biocotino I, Lim D, Grosa G, Galli U, Niemeyer B, Sorba G, Canonico PL, Cuzzocrea S, Genazzani AA, Pirali T. Riva B, et al. Among authors: serafini m. J Med Chem. 2018 Nov 8;61(21):9756-9783. doi: 10.1021/acs.jmedchem.8b01512. Epub 2018 Oct 30. J Med Chem. 2018. PMID: 30347159
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs.
Pirali T, Ciraolo E, Aprile S, Massarotti A, Berndt A, Griglio A, Serafini M, Mercalli V, Landoni C, Campa CC, Margaria JP, Silva RL, Grosa G, Sorba G, Williams R, Hirsch E, Tron GC. Pirali T, et al. Among authors: serafini m. ChemMedChem. 2017 Sep 21;12(18):1542-1554. doi: 10.1002/cmdc.201700340. Epub 2017 Aug 31. ChemMedChem. 2017. PMID: 28857471 Free PMC article.
Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders.
Serafini M, Griglio A, Aprile S, Seiti F, Travelli C, Pattarino F, Grosa G, Sorba G, Genazzani AA, Gonzalez-Rodriguez S, Butron L, Devesa I, Fernandez-Carvajal A, Pirali T, Ferrer-Montiel A. Serafini M, et al. J Med Chem. 2018 May 24;61(10):4436-4455. doi: 10.1021/acs.jmedchem.8b00109. Epub 2018 May 15. J Med Chem. 2018. PMID: 29722529
Applications of Deuterium in Medicinal Chemistry.
Pirali T, Serafini M, Cargnin S, Genazzani AA. Pirali T, et al. Among authors: serafini m. J Med Chem. 2019 Jun 13;62(11):5276-5297. doi: 10.1021/acs.jmedchem.8b01808. Epub 2019 Jan 25. J Med Chem. 2019. PMID: 30640460 Review.
Soft drugs for dermatological applications: recent trends.
Aprile S, Serafini M, Pirali T. Aprile S, et al. Among authors: serafini m. Drug Discov Today. 2019 Dec;24(12):2234-2246. doi: 10.1016/j.drudis.2019.08.007. Epub 2019 Sep 5. Drug Discov Today. 2019. PMID: 31494188 Review.
706 results