Song JL - Search Results

1

Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors.

Zhu K, Song JL, Tao HR, Cheng ZQ, Jiang CS, Zhang H. Zhu K, et al. Among authors: song jl. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3693-3699. doi: 10.1016/j.bmcl.2018.10.026. Epub 2018 Oct 19. Bioorg Med Chem Lett. 2018. PMID: 30366617

2

Design and synthesis of pregnenolone/2-cyanoacryloyl conjugates with dual NF-κB inhibitory and anti-proliferative activities.

Song JL, Zhang J, Liu CL, Liu C, Zhu KK, Yang FF, Liu XG, Figueiró Longo JP, Alexandre Muehlmann L, Azevedo RB, Zhang YY, Guo YW, Jiang CS, Zhang H. Song JL, et al. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4682-4686. doi: 10.1016/j.bmcl.2017.09.013. Epub 2017 Sep 8. Bioorg Med Chem Lett. 2017. PMID: 28919340

3

Synthesis and Evaluation of New Potential Benzo[a]phenoxazinium Photosensitizers for Anticancer Photodynamic Therapy.

Zhang J, Tavares de Sousa Júnior W, Mello da Silva VC, Rodrigues MC, Vasconcelos Morais JA, Song JL, Cheng ZQ, Longo JPF, Bentes Azevedo R, Jiang CS, Alexandre Muehlmann L, Zhang H. Zhang J, et al. Among authors: song jl. Molecules. 2018 Jun 13;23(6):1436. doi: 10.3390/molecules23061436. Molecules. 2018. PMID: 29899273 Free PMC article.

4

Synthesis and evaluation of coumarin/1,2,4-oxadiazole hybrids as selective BChE inhibitors with neuroprotective activity.

Zhang J, Li JC, Song JL, Cheng ZQ, Sun JZ, Jiang CS. Zhang J, et al. Among authors: song jl. J Asian Nat Prod Res. 2019 Nov;21(11):1090-1103. doi: 10.1080/10286020.2018.1492566. Epub 2018 Jul 10. J Asian Nat Prod Res. 2019. PMID: 29991292

5

Design, Synthesis, and Antiproliferative Evaluation of Novel Coumarin/2-Cyanoacryloyl Hybrids as Apoptosis Inducing Agents by Activation of Caspase-Dependent Pathway.

Zhang YY, Zhang QQ, Song JL, Zhang L, Jiang CS, Zhang H. Zhang YY, et al. Among authors: song jl. Molecules. 2018 Aug 7;23(8):1972. doi: 10.3390/molecules23081972. Molecules. 2018. PMID: 30087276 Free PMC article.

6

Total Synthesis of Pulmonarin B and Design of Brominated Phenylacetic Acid/Tacrine Hybrids: Marine Pharmacophore Inspired Discovery of New ChE and Aβ Aggregation Inhibitors.

Cheng ZQ, Song JL, Zhu K, Zhang J, Jiang CS, Zhang H. Cheng ZQ, et al. Among authors: song jl. Mar Drugs. 2018 Aug 21;16(9):293. doi: 10.3390/md16090293. Mar Drugs. 2018. PMID: 30134630 Free PMC article.

7

Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations.

Zhu K, Tao H, Song JL, Jin L, Zhang Y, Liu J, Chen Z, Jiang CS, Luo C, Zhang H. Zhu K, et al. Among authors: song jl. Bioorg Chem. 2018 Dec;81:289-298. doi: 10.1016/j.bioorg.2018.08.021. Epub 2018 Aug 20. Bioorg Chem. 2018. PMID: 30172110

8

Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors.

Cheng ZQ, Zhu KK, Zhang J, Song JL, Muehlmann LA, Jiang CS, Liu CL, Zhang H. Cheng ZQ, et al. Among authors: song jl. Bioorg Chem. 2019 Mar;83:277-288. doi: 10.1016/j.bioorg.2018.10.057. Epub 2018 Oct 29. Bioorg Chem. 2019. PMID: 30391700

9

Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation.

Jiang CS, Ge YX, Cheng ZQ, Song JL, Wang YY, Zhu K, Zhang H. Jiang CS, et al. Among authors: song jl. J Comput Aided Mol Des. 2019 May;33(5):521-530. doi: 10.1007/s10822-019-00202-2. Epub 2019 Apr 15. J Comput Aided Mol Des. 2019. PMID: 30989573

10

Design, Synthesis and Biological Evaluation of Novel Coumarin-Based Hydroxamate Derivatives as Histone Deacetylase (Hdac) Inhibitors with Antitumor Activities.

Yang F, Zhao N, Song J, Zhu K, Jiang CS, Shan P, Zhang H. Yang F, et al. Molecules. 2019 Jul 15;24(14):2569. doi: 10.3390/molecules24142569. Molecules. 2019. PMID: 31311163 Free PMC article.

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