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Multi-omics subtyping pipeline for chronic obstructive pulmonary disease.
Gillenwater LA, Helmi S, Stene E, Pratte KA, Zhuang Y, Schuyler RP, Lange L, Castaldi PJ, Hersh CP, Banaei-Kashani F, Bowler RP, Kechris KJ. Gillenwater LA, et al. Among authors: lange l. PLoS One. 2021 Aug 25;16(8):e0255337. doi: 10.1371/journal.pone.0255337. eCollection 2021. PLoS One. 2021. PMID: 34432807 Free PMC article.
Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol.
Wu P, Moon JY, Daghlas I, Franco G, Porneala BC, Ahmadizar F, Richardson TG, Isaksen JL, Hindy G, Yao J, Sitlani CM, Raffield LM, Yanek LR, Feitosa MF, Cuadrat RRC, Qi Q, Arfan Ikram M, Ellervik C, Ericson U, Goodarzi MO, Brody JA, Lange L, Mercader JM, Vaidya D, An P, Schulze MB, Masana L, Ghanbari M, Olesen MS, Cai J, Guo X, Floyd JS, Jäger S, Province MA, Kalyani RR, Psaty BM, Orho-Melander M, Ridker PM, Kanters JK, Uitterlinden A, Davey Smith G, Gill D, Kaplan RC, Kavousi M, Raghavan S, Chasman DI, Rotter JI, Meigs JB, Florez JC, Dupuis J, Liu CT, Merino J. Wu P, et al. Among authors: lange l. Diabetes Care. 2022 Jan 1;45(1):232-240. doi: 10.2337/dc21-1284. Diabetes Care. 2022. PMID: 34789503 Free PMC article.
Large scale proteomic studies create novel privacy considerations.
Hill AC, Guo C, Litkowski EM, Manichaikul AW, Yu B, Konigsberg IR, Gorbet BA, Lange LA, Pratte KA, Kechris KJ, DeCamp M, Coors M, Ortega VE, Rich SS, Rotter JI, Gerzsten RE, Clish CB, Curtis JL, Hu X, Obeidat ME, Morris M, Loureiro J, Ngo D, O'Neal WK, Meyers DA, Bleecker ER, Hobbs BD, Cho MH, Banaei-Kashani F, Bowler RP. Hill AC, et al. Among authors: lange la. Sci Rep. 2023 Jun 7;13(1):9254. doi: 10.1038/s41598-023-34866-6. Sci Rep. 2023. PMID: 37286633 Free PMC article.
Mendelian randomization study of diabetes and dementia in the Million Veteran Program.
Litkowski EM, Logue MW, Zhang R, Charest BR, Lange EM, Hokanson JE, Lynch JA, Vujkovic M, Phillips LS, Hauger RL, Lange LA, Raghavan S; VA Million Veteran Program (MVP). Litkowski EM, et al. Among authors: lange la, lange em. Alzheimers Dement. 2023 Oct;19(10):4367-4376. doi: 10.1002/alz.13373. Epub 2023 Jul 7. Alzheimers Dement. 2023. PMID: 37417779 Free PMC article.
Proteomic networks and related genetic variants associated with smoking and chronic obstructive pulmonary disease.
Konigsberg IR, Vu T, Liu W, Litkowski EM, Pratte KA, Vargas LB, Gilmore N, Abdel-Hafiz M, Manichaikul A, Cho MH, Hersh CP, DeMeo DL, Banaei-Kashani F, Bowler RP, Lange LA, Kechris KJ. Konigsberg IR, et al. Among authors: lange la. BMC Genomics. 2024 Sep 2;25(1):825. doi: 10.1186/s12864-024-10619-1. BMC Genomics. 2024. PMID: 39223457 Free PMC article.
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group; O'Connor TD. Kessler MD, et al. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117. Epub 2020 Jan 21. Proc Natl Acad Sci U S A. 2020. PMID: 31964835 Free PMC article.
Protein prediction for trait mapping in diverse populations.
Schubert R, Geoffroy E, Gregga I, Mulford AJ, Aguet F, Ardlie K, Gerszten R, Clish C, Van Den Berg D, Taylor KD, Durda P, Johnson WC, Cornell E, Guo X, Liu Y, Tracy R, Conomos M, Blackwell T, Papanicolaou G, Lappalainen T, Mikhaylova AV, Thornton TA, Cho MH, Gignoux CR, Lange L, Lange E, Rich SS, Rotter JI; NHLBI TOPMed Consortium; Manichaikul A, Im HK, Wheeler HE. Schubert R, et al. Among authors: lange l, lange e. PLoS One. 2022 Feb 24;17(2):e0264341. doi: 10.1371/journal.pone.0264341. eCollection 2022. PLoS One. 2022. PMID: 35202437 Free PMC article.
944 results