Iranzo J - Search Results

1

Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development.

Uehara R, Cerritelli SM, Hasin N, Sakhuja K, London M, Iranzo J, Chon H, Grinberg A, Crouch RJ. Uehara R, et al. Among authors: iranzo j. Cell Rep. 2018 Oct 30;25(5):1135-1145.e5. doi: 10.1016/j.celrep.2018.10.019. Cell Rep. 2018. PMID: 30380406 Free PMC article.

2

Competition among networks highlights the power of the weak.

Iranzo J, Buldú JM, Aguirre J. Iranzo J, et al. Nat Commun. 2016 Nov 14;7:13273. doi: 10.1038/ncomms13273. Nat Commun. 2016. PMID: 27841258 Free PMC article.

3

A network analysis of the human T-cell activation gene network identifies JAGGED1 as a therapeutic target for autoimmune diseases.

Palacios R, Goni J, Martinez-Forero I, Iranzo J, Sepulcre J, Melero I, Villoslada P. Palacios R, et al. Among authors: iranzo j. PLoS One. 2007 Nov 21;2(11):e1222. doi: 10.1371/journal.pone.0001222. PLoS One. 2007. PMID: 18030350 Free PMC article.

4

Genomes of the "Candidatus Actinomarinales" Order: Highly Streamlined Marine Epipelagic Actinobacteria.

López-Pérez M, Haro-Moreno JM, Iranzo J, Rodriguez-Valera F. López-Pérez M, et al. Among authors: iranzo j. mSystems. 2020 Dec 15;5(6):e01041-20. doi: 10.1128/mSystems.01041-20. mSystems. 2020. PMID: 33323418 Free PMC article.

5

High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase.

Cerritelli SM, Iranzo J, Sharma S, Chabes A, Crouch RJ, Tollervey D, El Hage A. Cerritelli SM, et al. Among authors: iranzo j. Nucleic Acids Res. 2020 May 7;48(8):4274-4297. doi: 10.1093/nar/gkaa103. Nucleic Acids Res. 2020. PMID: 32187369 Free PMC article.

6

Pervasive conditional selection of driver mutations and modular epistasis networks in cancer.

Iranzo J, Gruenhagen G, Calle-Espinosa J, Koonin EV. Iranzo J, et al. Cell Rep. 2022 Aug 23;40(8):111272. doi: 10.1016/j.celrep.2022.111272. Cell Rep. 2022. PMID: 36001960 Free article.

7

Evolutionary dynamics of the prokaryotic adaptive immunity system CRISPR-Cas in an explicit ecological context.

Iranzo J, Lobkovsky AE, Wolf YI, Koonin EV. Iranzo J, et al. J Bacteriol. 2013 Sep;195(17):3834-44. doi: 10.1128/JB.00412-13. Epub 2013 Jun 21. J Bacteriol. 2013. PMID: 23794616 Free PMC article.

8

Virus-host arms race at the joint origin of multicellularity and programmed cell death.

Iranzo J, Lobkovsky AE, Wolf YI, Koonin EV. Iranzo J, et al. Cell Cycle. 2014;13(19):3083-8. doi: 10.4161/15384101.2014.949496. Cell Cycle. 2014. PMID: 25486567 Free PMC article.

9

Immunity, suicide or both? Ecological determinants for the combined evolution of anti-pathogen defense systems.

Iranzo J, Lobkovsky AE, Wolf YI, Koonin EV. Iranzo J, et al. BMC Evol Biol. 2015 Mar 13;15:43. doi: 10.1186/s12862-015-0324-2. BMC Evol Biol. 2015. PMID: 25881094 Free PMC article.

10

The Double-Stranded DNA Virosphere as a Modular Hierarchical Network of Gene Sharing.

Iranzo J, Krupovic M, Koonin EV. Iranzo J, et al. mBio. 2016 Aug 2;7(4):e00978-16. doi: 10.1128/mBio.00978-16. mBio. 2016. PMID: 27486193 Free PMC article.

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