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Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance.
Zhou D, Zhang Y, Wu H, Barry E, Yin Y, Lawrence E, Dawson D, Willis JE, Markowitz SD, Camargo FD, Avruch J. Zhou D, et al. Among authors: avruch j. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):E1312-20. doi: 10.1073/pnas.1110428108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042863 Free PMC article.
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.
Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, Hong L, Xie C, Li X, Zhao H, Liu Q, Jiang M, Chen Q, Zhang J, Li Y, Song S, Wang HR, Zhou R, Johnson RL, Chien KY, Lin SC, Han J, Avruch J, Chen L, Zhou D. Geng J, et al. Among authors: avruch j. Nat Immunol. 2015 Nov;16(11):1142-52. doi: 10.1038/ni.3268. Epub 2015 Sep 28. Nat Immunol. 2015. PMID: 26414765 Free PMC article.
Protein kinases of the Hippo pathway: regulation and substrates.
Avruch J, Zhou D, Fitamant J, Bardeesy N, Mou F, Barrufet LR. Avruch J, et al. Semin Cell Dev Biol. 2012 Sep;23(7):770-84. doi: 10.1016/j.semcdb.2012.07.002. Epub 2012 Aug 9. Semin Cell Dev Biol. 2012. PMID: 22898666 Free PMC article. Review.
204 results