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Remote optimization of an ultracold atoms experiment by experts and citizen scientists.
Heck R, Vuculescu O, Sørensen JJ, Zoller J, Andreasen MG, Bason MG, Ejlertsen P, Elíasson O, Haikka P, Laustsen JS, Nielsen LL, Mao A, Müller R, Napolitano M, Pedersen MK, Thorsen AR, Bergenholtz C, Calarco T, Montangero S, Sherson JF. Heck R, et al. Among authors: mao a. Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11231-E11237. doi: 10.1073/pnas.1716869115. Epub 2018 Nov 9. Proc Natl Acad Sci U S A. 2018. PMID: 30413625 Free PMC article.
Elucidating the Phase I metabolism of psilocin in vitro.
Chen J, Wang Z, Yong CY, Goh EML, Moy HY, Chan ECY. Chen J, et al. Arch Toxicol. 2025 Jan 3. doi: 10.1007/s00204-024-03952-7. Online ahead of print. Arch Toxicol. 2025. PMID: 39751877
We identified 2-(4-hydroxy-1H-indol-3-yl)-acetaldehyde (4-HIA) as the Phase I intermediate metabolite for the first time. Psilocin was metabolized to 4-HIA by monoamine oxidase A (MAO-A), and further metabolized to the terminal metabolite 2-(4-hydroxy- …
We identified 2-(4-hydroxy-1H-indol-3-yl)-acetaldehyde (4-HIA) as the Phase I intermediate metabolite for the first time. Psilocin was metab …
Evolutionary and Functional Analysis of Monoamine Oxidase F (MAO F): A Novel Member of the MAO Gene Family.
Merello Oyarzún G, Olivares-Costa M, Basile L, Pástor TP, Mendoza-Soto P, Padilla-Santiago L, Mardones GA, Binda C, Opazo JC. Merello Oyarzún G, et al. Genome Biol Evol. 2025 Jan 3:evae280. doi: 10.1093/gbe/evae280. Online ahead of print. Genome Biol Evol. 2025. PMID: 39749937
The monoamine oxidase (MAO) gene family encodes for enzymes that perform the oxidative deamination of monoamines, a process required to degrade norepinephrine, serotonin, dopamine, and other amines. ...Thus, most jawed vertebrates possess a repertoire of two MAO gen …
The monoamine oxidase (MAO) gene family encodes for enzymes that perform the oxidative deamination of monoamines, a process re …
A monoamine oxidase B inhibitor altered gene expression of catalytically active dual-specificity phosphatases in human oral gingival keratinocytes.
Ostadkarampour M, Putnins EE. Ostadkarampour M, et al. Eur Rev Med Pharmacol Sci. 2024 Dec;28(24):4681-4690. doi: 10.26355/eurrev_202412_37002. Eur Rev Med Pharmacol Sci. 2024. PMID: 39749374
OBJECTIVE: Monoamine oxidase (MAO) inhibitors reduce inflammation in a number of in vitro and in vivo models. ...
OBJECTIVE: Monoamine oxidase (MAO) inhibitors reduce inflammation in a number of in vitro and in vivo models. ...
Haplotype-Resolved Genotyping and Association Analysis of 1,020 β-Thalassemia Patients by Targeted Long-Read Sequencing.
Ye Y, Niu C, Mao A, Qin L, Zhan J, Chen W, Liu Z, Xie T, Zhang Q, Li J, Huang L, Meng W, Liu Y, Liao L, Cai J, Liu R, Zhang X, Zeng L, Li Y, Lin B, Li K, Hua X, Huang B, Qin H, Huang Y, Huang Z, Lao J, Qu X, Chen J, Feng X, Liu Q, Lin W, Zhou X, Liang Y, Long X, Qin J, Yan L, Zhu W, Yu L, Fan C, Tang D, Zhong T, Tan J, Ren Z, Xu X. Ye Y, et al. Adv Sci (Weinh). 2024 Dec 31:e2410992. doi: 10.1002/advs.202410992. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 39737841
New class of thio/semicarbazide-based benzyloxy derivatives as selective class of monoamine oxidase-B inhibitors.
Chandran N, Lee J, Prabhakaran P, Kumar S, Sudevan ST, Parambi DGT, Alsahli TG, Pant M, Kim H, Mathew B. Chandran N, et al. Sci Rep. 2024 Dec 28;14(1):31292. doi: 10.1038/s41598-024-82771-3. Sci Rep. 2024. PMID: 39732801 Free PMC article.
Sixteen thio/semicarbazide-based benzyloxy derivatives (BT1-BT16) were synthesized and evaluated for their inhibitory activities against monoamine oxidases (MAOs). Most compounds showed better inhibitory activity against MAO-B than against MAO-A. ...
Sixteen thio/semicarbazide-based benzyloxy derivatives (BT1-BT16) were synthesized and evaluated for their inhibitory activities against …
Effects of MAO‑B inhibitors in life quality of Parkinson's disease patients: A systematic review and meta‑analysis.
Liu X, Su J, Zhang J, Li Z, Huang K, Lin D, Tao E. Liu X, et al. Behav Brain Res. 2024 Dec 26;480:115410. doi: 10.1016/j.bbr.2024.115410. Online ahead of print. Behav Brain Res. 2024. PMID: 39732440
INTRODUCTION: Monoamine oxidase-B (MAO-B) inhibitors, as an add-on therapy to levodopa, are widely used in Parkinson's disease (PD). ...
INTRODUCTION: Monoamine oxidase-B (MAO-B) inhibitors, as an add-on therapy to levodopa, are widely used in Parkinson's disease …
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