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BHLHA15-Positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice.
Hayakawa Y, Tsuboi M, Asfaha S, Kinoshita H, Niikura R, Konishi M, Hata M, Oya Y, Kim W, Middelhoff M, Hikiba Y, Higashijima N, Ihara S, Ushiku T, Fukayama M, Tailor Y, Hirata Y, Guha C, Yan KS, Koike K, Wang TC. Hayakawa Y, et al. Among authors: koike k. Gastroenterology. 2019 Mar;156(4):1066-1081.e16. doi: 10.1053/j.gastro.2018.11.024. Epub 2018 Nov 15. Gastroenterology. 2019. PMID: 30448068 Free PMC article.
Mature gastric chief cells are not required for the development of metaplasia.
Kinoshita H, Hayakawa Y, Niu Z, Konishi M, Hata M, Tsuboi M, Hayata Y, Hikiba Y, Ihara S, Nakagawa H, Hirata Y, Wang TC, Koike K. Kinoshita H, et al. Among authors: koike k. Am J Physiol Gastrointest Liver Physiol. 2018 May 1;314(5):G583-G596. doi: 10.1152/ajpgi.00351.2017. Epub 2018 Jan 18. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 29345968 Free PMC article.
GPR30-Expressing Gastric Chief Cells Do Not Dedifferentiate But Are Eliminated via PDK-Dependent Cell Competition During Development of Metaplasia.
Hata M, Kinoshita H, Hayakawa Y, Konishi M, Tsuboi M, Oya Y, Kurokawa K, Hayata Y, Nakagawa H, Tateishi K, Fujiwara H, Hirata Y, Worthley DL, Muranishi Y, Furukawa T, Kon S, Tomita H, Wang TC, Koike K. Hata M, et al. Among authors: koike k. Gastroenterology. 2020 May;158(6):1650-1666.e15. doi: 10.1053/j.gastro.2020.01.046. Epub 2020 Feb 4. Gastroenterology. 2020. PMID: 32032583 Free PMC article.
Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling.
Hayakawa Y, Sakitani K, Konishi M, Asfaha S, Niikura R, Tomita H, Renz BW, Tailor Y, Macchini M, Middelhoff M, Jiang Z, Tanaka T, Dubeykovskaya ZA, Kim W, Chen X, Urbanska AM, Nagar K, Westphalen CB, Quante M, Lin CS, Gershon MD, Hara A, Zhao CM, Chen D, Worthley DL, Koike K, Wang TC. Hayakawa Y, et al. Among authors: koike k. Cancer Cell. 2017 Jan 9;31(1):21-34. doi: 10.1016/j.ccell.2016.11.005. Epub 2016 Dec 15. Cancer Cell. 2017. PMID: 27989802 Free PMC article.
Metaplasia in the Stomach-Precursor of Gastric Cancer?
Kinoshita H, Hayakawa Y, Koike K. Kinoshita H, et al. Among authors: koike k. Int J Mol Sci. 2017 Sep 27;18(10):2063. doi: 10.3390/ijms18102063. Int J Mol Sci. 2017. PMID: 28953255 Free PMC article. Review.
3,119 results