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Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency.
Leipnitz G, Mohsen AW, Karunanidhi A, Seminotti B, Roginskaya VY, Markantone DM, Grings M, Mihalik SJ, Wipf P, Van Houten B, Vockley J. Leipnitz G, et al. Among authors: van houten b. Sci Rep. 2018 Jan 18;8(1):1165. doi: 10.1038/s41598-018-19543-3. Sci Rep. 2018. PMID: 29348607 Free PMC article.
Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers.
Seminotti B, Leipnitz G, Karunanidhi A, Kochersperger C, Roginskaya VY, Basu S, Wang Y, Wipf P, Van Houten B, Mohsen AW, Vockley J. Seminotti B, et al. Among authors: van houten b. Hum Mol Genet. 2019 Mar 15;28(6):928-941. doi: 10.1093/hmg/ddy403. Hum Mol Genet. 2019. PMID: 30445591 Free PMC article.
Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction.
Qian W, Kumar N, Roginskaya V, Fouquerel E, Opresko PL, Shiva S, Watkins SC, Kolodieznyi D, Bruchez MP, Van Houten B. Qian W, et al. Among authors: van houten b. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18435-18444. doi: 10.1073/pnas.1910574116. Epub 2019 Aug 26. Proc Natl Acad Sci U S A. 2019. PMID: 31451640 Free PMC article.
281 results