Rothwell N - Search Results

1

Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons.

Wong R, Lénárt N, Hill L, Toms L, Coutts G, Martinecz B, Császár E, Nyiri G, Papaemmanouil A, Waisman A, Müller W, Schwaninger M, Rothwell N, Francis S, Pinteaux E, Denés A, Allan SM. Wong R, et al. Among authors: rothwell n. Brain Behav Immun. 2019 Feb;76:126-138. doi: 10.1016/j.bbi.2018.11.012. Epub 2018 Nov 16. Brain Behav Immun. 2019. PMID: 30453020 Free PMC article.

2

Interleukin-1 and neuronal injury.

Allan SM, Tyrrell PJ, Rothwell NJ. Allan SM, et al. Nat Rev Immunol. 2005 Aug;5(8):629-40. doi: 10.1038/nri1664. Nat Rev Immunol. 2005. PMID: 16034365 Review.

3

Neuronal injury induces the release of pro-interleukin-1beta from activated microglia in vitro.

Wang P, Rothwell NJ, Pinteaux E, Brough D. Wang P, et al. Brain Res. 2008 Oct 21;1236:1-7. doi: 10.1016/j.brainres.2008.08.001. Epub 2008 Aug 8. Brain Res. 2008. PMID: 18722361

4

Brain inflammation is induced by co-morbidities and risk factors for stroke.

Drake C, Boutin H, Jones MS, Denes A, McColl BW, Selvarajah JR, Hulme S, Georgiou RF, Hinz R, Gerhard A, Vail A, Prenant C, Julyan P, Maroy R, Brown G, Smigova A, Herholz K, Kassiou M, Crossman D, Francis S, Proctor SD, Russell JC, Hopkins SJ, Tyrrell PJ, Rothwell NJ, Allan SM. Drake C, et al. Brain Behav Immun. 2011 Aug;25(6):1113-22. doi: 10.1016/j.bbi.2011.02.008. Epub 2011 Feb 26. Brain Behav Immun. 2011. PMID: 21356305 Free PMC article.

5

Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice.

Denes A, Wilkinson F, Bigger B, Chu M, Rothwell NJ, Allan SM. Denes A, et al. Dis Model Mech. 2013 Jul;6(4):1043-8. doi: 10.1242/dmm.011601. Epub 2013 Mar 15. Dis Model Mech. 2013. PMID: 23519030 Free PMC article.

6

Interleukin-1 as a pharmacological target in acute brain injury.

Brough D, Rothwell NJ, Allan SM. Brough D, et al. Exp Physiol. 2015 Dec;100(12):1488-94. doi: 10.1113/EP085135. Epub 2015 Jul 14. Exp Physiol. 2015. PMID: 26096539 Free article. Review.

7

Characterization of a conditional interleukin-1 receptor 1 mouse mutant using the Cre/LoxP system.

Abdulaal WH, Walker CR, Costello R, Redondo-Castro E, Mufazalov IA, Papaemmanouil A, Rothwell NJ, Allan SM, Waisman A, Pinteaux E, Müller W. Abdulaal WH, et al. Eur J Immunol. 2016 Apr;46(4):912-8. doi: 10.1002/eji.201546075. Epub 2016 Jan 18. Eur J Immunol. 2016. PMID: 26692072 Free PMC article.

8

Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia.

Pradillo JM, Murray KN, Coutts GA, Moraga A, Oroz-Gonjar F, Boutin H, Moro MA, Lizasoain I, Rothwell NJ, Allan SM. Pradillo JM, et al. Among authors: rothwell nj. Brain Behav Immun. 2017 Mar;61:117-126. doi: 10.1016/j.bbi.2016.11.013. Epub 2016 Nov 14. Brain Behav Immun. 2017. PMID: 27856349 Free PMC article.

9

Inflammation and brain injury: acute cerebral ischaemia, peripheral and central inflammation.

Denes A, Thornton P, Rothwell NJ, Allan SM. Denes A, et al. Among authors: rothwell nj. Brain Behav Immun. 2010 Jul;24(5):708-23. doi: 10.1016/j.bbi.2009.09.010. Epub 2009 Sep 19. Brain Behav Immun. 2010. PMID: 19770034 Review.

10

AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.

Denes A, Coutts G, Lénárt N, Cruickshank SM, Pelegrin P, Skinner J, Rothwell N, Allan SM, Brough D. Denes A, et al. Among authors: rothwell n. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4050-5. doi: 10.1073/pnas.1419090112. Epub 2015 Mar 16. Proc Natl Acad Sci U S A. 2015. PMID: 25775556 Free PMC article.

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