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Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons.
Wong R, Lénárt N, Hill L, Toms L, Coutts G, Martinecz B, Császár E, Nyiri G, Papaemmanouil A, Waisman A, Müller W, Schwaninger M, Rothwell N, Francis S, Pinteaux E, Denés A, Allan SM. Wong R, et al. Brain Behav Immun. 2019 Feb;76:126-138. doi: 10.1016/j.bbi.2018.11.012. Epub 2018 Nov 16. Brain Behav Immun. 2019. PMID: 30453020 Free PMC article.
A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke.
Maysami S, Wong R, Pradillo JM, Denes A, Dhungana H, Malm T, Koistinaho J, Orset C, Rahman M, Rubio M, Schwaninger M, Vivien D, Bath PM, Rothwell NJ, Allan SM. Maysami S, et al. Among authors: wong r. J Cereb Blood Flow Metab. 2016 Mar;36(3):596-605. doi: 10.1177/0271678X15606714. Epub 2015 Sep 30. J Cereb Blood Flow Metab. 2016. PMID: 26661169 Free PMC article.
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.
Daniels MJ, Rivers-Auty J, Schilling T, Spencer NG, Watremez W, Fasolino V, Booth SJ, White CS, Baldwin AG, Freeman S, Wong R, Latta C, Yu S, Jackson J, Fischer N, Koziel V, Pillot T, Bagnall J, Allan SM, Paszek P, Galea J, Harte MK, Eder C, Lawrence CB, Brough D. Daniels MJ, et al. Among authors: wong r. Nat Commun. 2016 Aug 11;7:12504. doi: 10.1038/ncomms12504. Nat Commun. 2016. PMID: 27509875 Free PMC article.
β1 integrin is a sensor of blood flow direction.
Xanthis I, Souilhol C, Serbanovic-Canic J, Roddie H, Kalli AC, Fragiadaki M, Wong R, Shah DR, Askari JA, Canham L, Akhtar N, Feng S, Ridger V, Waltho J, Pinteaux E, Humphries MJ, Bryan MT, Evans PC. Xanthis I, et al. Among authors: wong r. J Cell Sci. 2019 Jun 3;132(11):jcs229542. doi: 10.1242/jcs.229542. J Cell Sci. 2019. PMID: 31076511 Free PMC article.
5,653 results