Ishak Gabra MB - Search Results

1

IKKβ activates p53 to promote cancer cell adaptation to glutamine deprivation.

Ishak Gabra MB, Yang Y, Lowman XH, Reid MA, Tran TQ, Kong M. Ishak Gabra MB, et al. Oncogenesis. 2018 Nov 26;7(11):93. doi: 10.1038/s41389-018-0104-0. Oncogenesis. 2018. PMID: 30478303 Free PMC article.

2

IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3.

Reid MA, Lowman XH, Pan M, Tran TQ, Warmoes MO, Ishak Gabra MB, Yang Y, Locasale JW, Kong M. Reid MA, et al. Among authors: ishak gabra mb. Genes Dev. 2016 Aug 15;30(16):1837-51. doi: 10.1101/gad.287235.116. Epub 2016 Sep 1. Genes Dev. 2016. PMID: 27585591 Free PMC article.

3

p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake.

Lowman XH, Hanse EA, Yang Y, Ishak Gabra MB, Tran TQ, Li H, Kong M. Lowman XH, et al. Among authors: ishak gabra mb. Cell Rep. 2019 Mar 12;26(11):3051-3060.e4. doi: 10.1016/j.celrep.2019.02.037. Cell Rep. 2019. PMID: 30865893 Free PMC article.

4

Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes.

Tran TQ, Ishak Gabra MB, Lowman XH, Yang Y, Reid MA, Pan M, O'Connor TR, Kong M. Tran TQ, et al. Among authors: ishak gabra mb. PLoS Biol. 2017 Nov 6;15(11):e2002810. doi: 10.1371/journal.pbio.2002810. eCollection 2017 Nov. PLoS Biol. 2017. PMID: 29107960 Free PMC article.

5

MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1.

Yang Y, Ishak Gabra MB, Hanse EA, Lowman XH, Tran TQ, Li H, Milman N, Liu J, Reid MA, Locasale JW, Gil Z, Kong M. Yang Y, et al. Among authors: ishak gabra mb. Nat Commun. 2019 Feb 18;10(1):809. doi: 10.1038/s41467-019-08759-0. Nat Commun. 2019. PMID: 30778058 Free PMC article.

6

Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.

Ishak Gabra MB, Yang Y, Li H, Senapati P, Hanse EA, Lowman XH, Tran TQ, Zhang L, Doan LT, Xu X, Schones DE, Fruman DA, Kong M. Ishak Gabra MB, et al. Nat Commun. 2020 Jul 3;11(1):3326. doi: 10.1038/s41467-020-17181-w. Nat Commun. 2020. PMID: 32620791 Free PMC article.

7

α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer.

Tran TQ, Hanse EA, Habowski AN, Li H, Ishak Gabra MB, Yang Y, Lowman XH, Ooi AM, Liao SY, Edwards RA, Waterman ML, Kong M. Tran TQ, et al. Among authors: ishak gabra mb. Nat Cancer. 2020 Mar;1(3):345-358. doi: 10.1038/s43018-020-0035-5. Epub 2020 Mar 20. Nat Cancer. 2020. PMID: 32832918 Free PMC article.

8

The B56α subunit of PP2A is necessary for mesenchymal stem cell commitment to adipocyte.

Hanse EA, Pan M, Liu W, Yang Y, Ishak Gabra MB, Tran TQ, Lowman XH, Ruiz B, Wang QA, Kong M. Hanse EA, et al. Among authors: ishak gabra mb. EMBO Rep. 2021 Aug 4;22(8):e51910. doi: 10.15252/embr.202051910. Epub 2021 Jul 7. EMBO Rep. 2021. PMID: 34232566 Free PMC article.

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