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Page 1
Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease.
Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW. Wilmanns JC, et al. Among authors: pearson jt. Mol Metab. 2019 Feb;20:102-114. doi: 10.1016/j.molmet.2018.11.002. Epub 2018 Nov 15. Mol Metab. 2019. PMID: 30482476 Free PMC article.
A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.
Furtado MB, Wilmanns JC, Chandran A, Tonta M, Biben C, Eichenlaub M, Coleman HA, Berger S, Bouveret R, Singh R, Harvey RP, Ramialison M, Pearson JT, Parkington HC, Rosenthal NA, Costa MW. Furtado MB, et al. Among authors: pearson jt. Differentiation. 2016 Jan-Mar;91(1-3):29-41. doi: 10.1016/j.diff.2015.12.003. Epub 2016 Feb 17. Differentiation. 2016. PMID: 26897459
Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.
Furtado MB, Wilmanns JC, Chandran A, Perera J, Hon O, Biben C, Willow TJ, Nim HT, Kaur G, Simonds S, Wu Q, Willians D, Salimova E, Plachta N, Denegre JM, Murray SA, Fatkin D, Cowley M, Pearson JT, Kaye D, Ramialison M, Harvey RP, Rosenthal NA, Costa MW. Furtado MB, et al. Among authors: pearson jt. JCI Insight. 2017 Mar 23;2(6):e88271. doi: 10.1172/jci.insight.88271. JCI Insight. 2017. PMID: 28352650 Free PMC article.
Diffusion Tensor Imaging Colour Mapping Threshold for Identification of Ventilation-Induced Brain Injury after Intrauterine Inflammation in Preterm Lambs.
Alahmari DM, Skiöld B, Barton SK, Nitsos I, McDonald C, Miller SL, Zahra V, Galinsky R, Wu Q, Farrell MJ, Moss TJ, Hooper SB, Pearson JT, Polglase GR. Alahmari DM, et al. Among authors: pearson jt. Front Pediatr. 2017 Apr 5;5:70. doi: 10.3389/fped.2017.00070. eCollection 2017. Front Pediatr. 2017. PMID: 28424764 Free PMC article.
Diastolic dysfunction is initiated by cardiomyocyte impairment ahead of endothelial dysfunction due to increased oxidative stress and inflammation in an experimental prediabetes model.
Waddingham MT, Sonobe T, Tsuchimochi H, Edgley AJ, Sukumaran V, Chen YC, Hansra SS, Schwenke DO, Umetani K, Aoyama K, Yagi N, Kelly DJ, Gaderi S, Herwig M, Kolijn D, Mügge A, Paulus WJ, Ogo T, Shirai M, Hamdani N, Pearson JT. Waddingham MT, et al. Among authors: pearson jt. J Mol Cell Cardiol. 2019 Dec;137:119-131. doi: 10.1016/j.yjmcc.2019.10.005. Epub 2019 Oct 28. J Mol Cell Cardiol. 2019. PMID: 31669609 Free article.
Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications.
Saw EL, Pearson JT, Schwenke DO, Munasinghe PE, Tsuchimochi H, Rawal S, Coffey S, Davis P, Bunton R, Van Hout I, Kai Y, Williams MJA, Kakinuma Y, Fronius M, Katare R. Saw EL, et al. Among authors: pearson jt. Cardiovasc Diabetol. 2021 Feb 22;20(1):50. doi: 10.1186/s12933-021-01231-8. Cardiovasc Diabetol. 2021. PMID: 33618724 Free PMC article.
200 results