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A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice.
Østergaard H, Lund J, Greisen PJ, Kjellev S, Henriksen A, Lorenzen N, Johansson E, Røder G, Rasch MG, Johnsen LB, Egebjerg T, Lund S, Rahbek-Nielsen H, Gandhi PS, Lamberth K, Loftager M, Andersen LM, Bonde AC, Stavenuiter F, Madsen DE, Li X, Holm TL, Ley CD, Thygesen P, Zhu H, Zhou R, Thorn K, Yang Z, Hermit MB, Bjelke JR, Hansen BG, Hilden I. Østergaard H, et al. Among authors: lund j, lund s. Blood. 2021 Oct 7;138(14):1258-1268. doi: 10.1182/blood.2020010331. Blood. 2021. PMID: 34077951 Free PMC article.
Nonspecificity fingerprints for clinical-stage antibodies in solution.
Herling TW, Invernizzi G, Ausserwöger H, Bjelke JR, Egebjerg T, Lund S, Lorenzen N, Knowles TPJ. Herling TW, et al. Among authors: lund s. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2306700120. doi: 10.1073/pnas.2306700120. Epub 2023 Dec 18. Proc Natl Acad Sci U S A. 2023. PMID: 38109540 Free PMC article.
Improving the Developability of an Antigen Binding Fragment by Aspartate Substitutions.
Sakhnini LI, Greisen PJ, Wiberg C, Bozoky Z, Lund S, Wolf Perez AM, Karkov HS, Huus K, Hansen JJ, Bülow L, Lorenzen N, Dainiak MB, Pedersen AK. Sakhnini LI, et al. Among authors: lund s. Biochemistry. 2019 Jun 18;58(24):2750-2759. doi: 10.1021/acs.biochem.9b00251. Epub 2019 Jun 5. Biochemistry. 2019. PMID: 31117388
Computational design of N-linked glycans for high throughput epitope profiling.
Greisen PJ, Yi L, Zhou R, Zhou J, Johansson E, Dong T, Liu H, Johnsen LB, Lund S, Svensson LA, Zhu H, Thomas N, Yang Z, Østergaard H. Greisen PJ, et al. Among authors: lund s. Protein Sci. 2023 Oct;32(10):e4726. doi: 10.1002/pro.4726. Protein Sci. 2023. PMID: 37421602 Free PMC article.
727 results