A human-derived antibody targets misfolded SOD1 and ameliorates motor symptoms in mouse models of amyotrophic lateral sclerosis.
Maier M, Welt T, Wirth F, Montrasio F, Preisig D, McAfoose J, Vieira FG, Kulic L, Späni C, Stehle T, Perrin S, Weber M, Hock C, Nitsch RM, Grimm J.
Maier M, et al. Among authors: preisig d.
Sci Transl Med. 2018 Dec 5;10(470):eaah3924. doi: 10.1126/scitranslmed.aah3924.
Sci Transl Med. 2018.
PMID: 30518612