Späni C - Search Results

1

A human-derived antibody targets misfolded SOD1 and ameliorates motor symptoms in mouse models of amyotrophic lateral sclerosis.

Maier M, Welt T, Wirth F, Montrasio F, Preisig D, McAfoose J, Vieira FG, Kulic L, Späni C, Stehle T, Perrin S, Weber M, Hock C, Nitsch RM, Grimm J. Maier M, et al. Among authors: spani c. Sci Transl Med. 2018 Dec 5;10(470):eaah3924. doi: 10.1126/scitranslmed.aah3924. Sci Transl Med. 2018. PMID: 30518612

2

Amyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer disease.

Hanenberg M, McAfoose J, Kulic L, Welt T, Wirth F, Parizek P, Strobel L, Cattepoel S, Späni C, Derungs R, Maier M, Plückthun A, Nitsch RM. Hanenberg M, et al. Among authors: spani c. J Biol Chem. 2014 Sep 26;289(39):27080-27089. doi: 10.1074/jbc.M114.564013. Epub 2014 Aug 12. J Biol Chem. 2014. PMID: 25118284 Free PMC article.

3

High-speed video gait analysis reveals early and characteristic locomotor phenotypes in mouse models of neurodegenerative movement disorders.

Preisig DF, Kulic L, Krüger M, Wirth F, McAfoose J, Späni C, Gantenbein P, Derungs R, Nitsch RM, Welt T. Preisig DF, et al. Among authors: spani c. Behav Brain Res. 2016 Sep 15;311:340-353. doi: 10.1016/j.bbr.2016.04.044. Epub 2016 May 24. Behav Brain Res. 2016. PMID: 27233823

4

Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation.

Kulic L, McAfoose J, Welt T, Tackenberg C, Späni C, Wirth F, Finder V, Konietzko U, Giese M, Eckert A, Noriaki K, Shimizu T, Murakami K, Irie K, Rasool S, Glabe C, Hock C, Nitsch RM. Kulic L, et al. Among authors: spani c. Transl Psychiatry. 2012 Nov 13;2(11):e183. doi: 10.1038/tp.2012.109. Transl Psychiatry. 2012. PMID: 23149447 Free PMC article.

5

Genetic ablation of the p66^Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease.

Derungs R, Camici GG, Spescha RD, Welt T, Tackenberg C, Späni C, Wirth F, Grimm A, Eckert A, Nitsch RM, Kulic L. Derungs R, et al. Among authors: spani c. Mol Psychiatry. 2017 Apr;22(4):605-614. doi: 10.1038/mp.2016.112. Epub 2016 Jul 19. Mol Psychiatry. 2017. PMID: 27431297

6

Acute Effects of Muscarinic M1 Receptor Modulation on AβPP Metabolism and Amyloid-β Levels in vivo: A Microdialysis Study.

Welt T, Kulic L, Hoey SE, McAfoose J, Späni C, Chadha AS, Fisher A, Nitsch RM. Welt T, et al. Among authors: spani c. J Alzheimers Dis. 2015;46(4):971-82. doi: 10.3233/JAD-150152. J Alzheimers Dis. 2015. PMID: 25881909

7

Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer's disease lacking functional B and T cells.

Späni C, Suter T, Derungs R, Ferretti MT, Welt T, Wirth F, Gericke C, Nitsch RM, Kulic L. Späni C, et al. Acta Neuropathol Commun. 2015 Nov 11;3:71. doi: 10.1186/s40478-015-0251-x. Acta Neuropathol Commun. 2015. PMID: 26558367 Free PMC article.

8

T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer's disease-like cerebral amyloidosis.

Ferretti MT, Merlini M, Späni C, Gericke C, Schweizer N, Enzmann G, Engelhardt B, Kulic L, Suter T, Nitsch RM. Ferretti MT, et al. Among authors: spani c. Brain Behav Immun. 2016 May;54:211-225. doi: 10.1016/j.bbi.2016.02.009. Epub 2016 Feb 9. Brain Behav Immun. 2016. PMID: 26872418 Free article.

9

Quality of life after traumatic brain injury: a cross-sectional analysis uncovers age- and sex-related differences over the adult life span.

Rauen K, Späni CB, Tartaglia MC, Ferretti MT, Reichelt L, Probst P, Schäpers B, Müller F, Jahn K, Plesnila N. Rauen K, et al. Among authors: spani cb. Geroscience. 2021 Feb;43(1):263-278. doi: 10.1007/s11357-020-00273-2. Epub 2020 Oct 17. Geroscience. 2021. PMID: 33070278 Free PMC article.

10

Sex-related responses after traumatic brain injury: Considerations for preclinical modeling.

Späni CB, Braun DJ, Van Eldik LJ. Späni CB, et al. Front Neuroendocrinol. 2018 Jul;50:52-66. doi: 10.1016/j.yfrne.2018.03.006. Epub 2018 May 18. Front Neuroendocrinol. 2018. PMID: 29753798 Free PMC article. Review.

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