Furukawa Y - Search Results

1

Biochemical and morphological classification of disease-associated alpha-synuclein mutants aggregates.

Tanaka G, Yamanaka T, Furukawa Y, Kajimura N, Mitsuoka K, Nukina N. Tanaka G, et al. Among authors: furukawa y. Biochem Biophys Res Commun. 2019 Jan 15;508(3):729-734. doi: 10.1016/j.bbrc.2018.11.200. Epub 2018 Dec 6. Biochem Biophys Res Commun. 2019. PMID: 30528390

2

RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells.

Doi H, Okamura K, Bauer PO, Furukawa Y, Shimizu H, Kurosawa M, Machida Y, Miyazaki H, Mitsui K, Kuroiwa Y, Nukina N. Doi H, et al. Among authors: furukawa y. J Biol Chem. 2008 Mar 7;283(10):6489-500. doi: 10.1074/jbc.M705306200. Epub 2007 Dec 31. J Biol Chem. 2008. PMID: 18167354 Free article.

3

Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis.

Furukawa Y, Kaneko K, Yamanaka K, O'Halloran TV, Nukina N. Furukawa Y, et al. J Biol Chem. 2008 Aug 29;283(35):24167-76. doi: 10.1074/jbc.M802083200. Epub 2008 Jun 13. J Biol Chem. 2008. PMID: 18552350 Free PMC article.

4

Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases.

Furukawa Y, Kaneko K, Matsumoto G, Kurosawa M, Nukina N. Furukawa Y, et al. J Neurosci. 2009 Apr 22;29(16):5153-62. doi: 10.1523/JNEUROSCI.0783-09.2009. J Neurosci. 2009. PMID: 19386911 Free PMC article.

5

Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction.

Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Furukawa Y, Yamada M, Nukina N. Yamanaka T, et al. Among authors: furukawa y. Hum Mol Genet. 2010 Jun 1;19(11):2099-112. doi: 10.1093/hmg/ddq087. Epub 2010 Feb 25. Hum Mol Genet. 2010. PMID: 20185558 Free PMC article.

6

Mutation-dependent polymorphism of Cu,Zn-superoxide dismutase aggregates in the familial form of amyotrophic lateral sclerosis.

Furukawa Y, Kaneko K, Yamanaka K, Nukina N. Furukawa Y, et al. J Biol Chem. 2010 Jul 16;285(29):22221-31. doi: 10.1074/jbc.M110.113597. Epub 2010 Apr 19. J Biol Chem. 2010. PMID: 20404329 Free PMC article.

7

A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions.

Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N. Furukawa Y, et al. J Biol Chem. 2011 May 27;286(21):18664-72. doi: 10.1074/jbc.M111.231209. Epub 2011 Mar 24. J Biol Chem. 2011. PMID: 21454603 Free PMC article.

8

Tau protein assembles into isoform- and disulfide-dependent polymorphic fibrils with distinct structural properties.

Furukawa Y, Kaneko K, Nukina N. Furukawa Y, et al. J Biol Chem. 2011 Aug 5;286(31):27236-46. doi: 10.1074/jbc.M111.248963. Epub 2011 Jun 9. J Biol Chem. 2011. PMID: 21659525 Free PMC article.

9

Molecular properties of TAR DNA binding protein-43 fragments are dependent upon its cleavage site.

Furukawa Y, Kaneko K, Nukina N. Furukawa Y, et al. Biochim Biophys Acta. 2011 Dec;1812(12):1577-83. doi: 10.1016/j.bbadis.2011.09.005. Epub 2011 Sep 16. Biochim Biophys Acta. 2011. PMID: 21946215 Free article.

10

Local unfolding of Cu, Zn superoxide dismutase monomer determines the morphology of fibrillar aggregates.

Ding F, Furukawa Y, Nukina N, Dokholyan NV. Ding F, et al. Among authors: furukawa y. J Mol Biol. 2012 Aug 24;421(4-5):548-60. doi: 10.1016/j.jmb.2011.12.029. Epub 2011 Dec 21. J Mol Biol. 2012. PMID: 22210350 Free PMC article.

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