Slusher BS - Search Results

1

DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.

Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer M, Slusher BS. Rojas C, et al. Among authors: slusher bs. Sci Rep. 2018 Dec 7;8(1):17715. doi: 10.1038/s41598-018-36144-2. Sci Rep. 2018. PMID: 30531925 Free PMC article.

2

Toxicity induced by a polyglutamated folate analog is attenuated by NAALADase inhibition.

Thomas AG, Olkowski JL, Vornov JJ, Slusher BS. Thomas AG, et al. Among authors: slusher bs. Brain Res. 1999 Oct 2;843(1-2):48-52. doi: 10.1016/s0006-8993(99)01879-x. Brain Res. 1999. PMID: 10528109

3

Blockade of NAALADase: a novel neuroprotective strategy based on limiting glutamate and elevating NAAG.

Vornov JJ, Wozniak K, Lu M, Jackson P, Tsukamoto T, Wang E, Slusher B. Vornov JJ, et al. Ann N Y Acad Sci. 1999;890:400-5. doi: 10.1111/j.1749-6632.1999.tb08019.x. Ann N Y Acad Sci. 1999. PMID: 10668445

4

N-Acetylated alpha-linked acidic dipeptidase converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin.

Thomas AG, Vornov JJ, Olkowski JL, Merion AT, Slusher BS. Thomas AG, et al. Among authors: slusher bs. J Pharmacol Exp Ther. 2000 Oct;295(1):16-22. J Pharmacol Exp Ther. 2000. PMID: 10991955

5

Expression and acquisition of the conditioned place preference response to cocaine in rats is blocked by selective inhibitors of the enzyme N-acetylated-alpha-linked-acidic dipeptidase (NAALADASE).

Slusher BS, Thomas A, Paul M, Schad CA, Ashby CR Jr. Slusher BS, et al. Synapse. 2001 Jul;41(1):22-8. doi: 10.1002/syn.1056. Synapse. 2001. PMID: 11354010

6

Neuroprotection afforded by NAAG and NAALADase inhibition requires glial cells and metabotropic glutamate receptor activation.

Thomas AG, Olkowski JL, Slusher BS. Thomas AG, et al. Among authors: slusher bs. Eur J Pharmacol. 2001 Aug 24;426(1-2):35-8. doi: 10.1016/s0014-2999(01)01198-0. Eur J Pharmacol. 2001. PMID: 11525768

7

Binding of the glutamate carboxypeptidase II (NAALADase) inhibitor 2-PMPA to rat brain membranes.

Tiffany CW, Cai NS, Rojas C, Slusher BS. Tiffany CW, et al. Among authors: slusher bs. Eur J Pharmacol. 2001 Sep 14;427(2):91-6. doi: 10.1016/s0014-2999(01)01236-5. Eur J Pharmacol. 2001. PMID: 11557259

8

Neuroprotection mediated by glutamate carboxypeptidase II (NAALADase) inhibition requires TGF-beta.

Thomas AG, Liu W, Olkowski JL, Tang Z, Lin Q, Lu XC, Slusher BS. Thomas AG, et al. Among authors: slusher bs. Eur J Pharmacol. 2001 Oct 26;430(1):33-40. doi: 10.1016/s0014-2999(01)01239-0. Eur J Pharmacol. 2001. PMID: 11698060

9

Phosphonate and phosphinate analogues of N-acylated gamma-glutamylglutamate. potent inhibitors of glutamate carboxypeptidase II.

Tsukamoto T, Flanary JM, Rojas C, Slusher BS, Valiaeva N, Coward JK. Tsukamoto T, et al. Among authors: slusher bs. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2189-92. doi: 10.1016/s0960-894x(02)00360-8. Bioorg Med Chem Lett. 2002. PMID: 12127534

10

Kinetics and inhibition of glutamate carboxypeptidase II using a microplate assay.

Rojas C, Frazier ST, Flanary J, Slusher BS. Rojas C, et al. Among authors: slusher bs. Anal Biochem. 2002 Nov 1;310(1):50-4. doi: 10.1016/s0003-2697(02)00286-5. Anal Biochem. 2002. PMID: 12413472

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