Guerrini R - Search Results

1

Probing the Effect of Sildenafil on Progesterone and Testosterone Production by an Intracellular FRET/BRET Combined Approach.

Casarini L, Riccetti L, Limoncella S, Lazzaretti C, Barbagallo F, Pacifico S, Guerrini R, Tagliavini S, Trenti T, Simoni M, Sola M, Di Rocco G. Casarini L, et al. Among authors: guerrini r. Biochemistry. 2019 Feb 12;58(6):799-808. doi: 10.1021/acs.biochem.8b01073. Epub 2018 Dec 21. Biochemistry. 2019. PMID: 30532959

2

In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative.

Ruzza C, Rizzi A, Malfacini D, Pulga A, Pacifico S, Salvadori S, Trapella C, Reinscheid RK, Calo G, Guerrini R. Ruzza C, et al. Among authors: guerrini r. Pharmacol Res Perspect. 2015 Feb;3(1):e00108. doi: 10.1002/prp2.108. Epub 2015 Jan 5. Pharmacol Res Perspect. 2015. PMID: 25692025 Free PMC article.

3

Structure activity studies of nociceptin/orphanin FQ(1-13)-NH2 derivatives modified in position 5.

Guerrini R, Marzola E, Trapella C, Pacifico S, Cerlesi MC, Malfacini D, Ferrari F, Bird MF, Lambert DG, Salvadori S, Calo G. Guerrini R, et al. Bioorg Med Chem. 2015 Apr 1;23(7):1515-20. doi: 10.1016/j.bmc.2015.02.008. Epub 2015 Feb 12. Bioorg Med Chem. 2015. PMID: 25716007

4

Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology.

Ponterini G, Martello A, Pavesi G, Lauriola A, Luciani R, Santucci M, Pelà M, Gozzi G, Pacifico S, Guerrini R, Marverti G, Costi MP, D'Arca D. Ponterini G, et al. Among authors: guerrini r. Sci Rep. 2016 Jun 2;6:27198. doi: 10.1038/srep27198. Sci Rep. 2016. PMID: 27250901 Free PMC article.

5

Neuropeptide S receptor ligands: a patent review (2005-2016).

Ruzza C, Calò G, Di Maro S, Pacifico S, Trapella C, Salvadori S, Preti D, Guerrini R. Ruzza C, et al. Among authors: guerrini r. Expert Opin Ther Pat. 2017 Mar;27(3):347-362. doi: 10.1080/13543776.2017.1254195. Epub 2016 Nov 9. Expert Opin Ther Pat. 2017. PMID: 27788040 Review.

6

Structure- and conformation-activity studies of nociceptin/orphanin FQ receptor dimeric ligands.

Pacifico S, Carotenuto A, Brancaccio D, Novellino E, Marzola E, Ferrari F, Cerlesi MC, Trapella C, Preti D, Salvadori S, Calò G, Guerrini R. Pacifico S, et al. Among authors: guerrini r. Sci Rep. 2017 Apr 6;7:45817. doi: 10.1038/srep45817. Sci Rep. 2017. PMID: 28383520 Free PMC article.

7

Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor.

Pacifico S, Kerckhoffs A, Fallow AJ, Foreman RE, Guerrini R, McDonald J, Lambert DG, Jamieson AG. Pacifico S, et al. Among authors: guerrini r. Org Biomol Chem. 2017 May 31;15(21):4704-4710. doi: 10.1039/c7ob00959c. Org Biomol Chem. 2017. PMID: 28524918 Free article.

8

A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism.

Fantinati A, Bianco S, Guerrini R, Salvadori S, Pacifico S, Cerlesi MC, Calo G, Trapella C. Fantinati A, et al. Among authors: guerrini r. Sci Rep. 2017 May 25;7(1):2416. doi: 10.1038/s41598-017-02502-9. Sci Rep. 2017. PMID: 28546566 Free PMC article.

9

Peptide welding technology - A simple strategy for generating innovative ligands for G protein coupled receptors.

Calo' G, Rizzi A, Ruzza C, Ferrari F, Pacifico S, Gavioli EC, Salvadori S, Guerrini R. Calo' G, et al. Among authors: guerrini r. Peptides. 2018 Jan;99:195-204. doi: 10.1016/j.peptides.2017.10.004. Epub 2017 Oct 13. Peptides. 2018. PMID: 29031796 Review.

10

Fluorometric detection of protein-ligand engagement: The case of phosphodiesterase5.

Di Rocco G, Martinelli I, Pacifico S, Guerrini R, Cichero E, Fossa P, Franchini S, Cardarelli S, Giorgi M, Sola M, Ponterini G. Di Rocco G, et al. Among authors: guerrini r. J Pharm Biomed Anal. 2018 Feb 5;149:335-342. doi: 10.1016/j.jpba.2017.11.014. Epub 2017 Nov 11. J Pharm Biomed Anal. 2018. PMID: 29132113 Free article.

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