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An activity-based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti-fibrotic therapeutic strategies.
Findlay A, Turner C, Schilter H, Deodhar M, Zhou W, Perryman L, Foot J, Zahoor A, Yao Y, Hamilton R, Brock M, Raso C, Stolp J, Galati M, Hamprecht D, Charlton B, Jarolimek W. Findlay A, et al. Among authors: zhou w. Clin Transl Med. 2021 Nov;11(11):e572. doi: 10.1002/ctm2.572. Clin Transl Med. 2021. PMID: 34841699 Free PMC article. No abstract available.
Chemically engineered antibodies for autophagy-based receptor degradation.
Cheng B, Li M, Zheng J, Liang J, Li Y, Liang R, Tian H, Zhou Z, Ding L, Ren J, Shi W, Zhou W, Hu H, Meng L, Liu K, Cai L, Shao X, Fang L, Li H. Cheng B, et al. Among authors: zhou w. Nat Chem Biol. 2025 Jan 9. doi: 10.1038/s41589-024-01803-1. Online ahead of print. Nat Chem Biol. 2025. PMID: 39789191
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