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Characteristics of genomic alterations of lung adenocarcinoma in young never-smokers.
Luo W, Tian P, Wang Y, Xu H, Chen L, Tang C, Shu Y, Zhang S, Wang Z, Zhang J, Zhang L, Jiang L, Liu L, Che G, Guo C, Zhang H, Wang J, Li W. Luo W, et al. Among authors: chen l. Int J Cancer. 2018 Oct 1;143(7):1696-1705. doi: 10.1002/ijc.31542. Epub 2018 May 7. Int J Cancer. 2018. PMID: 29667179 Free PMC article.
Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response.
Lin JW, Tang C, Wei HC, Du B, Chen C, Wang M, Zhou Y, Yu MX, Cheng L, Kuivanen S, Ogando NS, Levanov L, Zhao Y, Li CL, Zhou R, Li Z, Zhang Y, Sun K, Wang C, Chen L, Xiao X, Zheng X, Chen SS, Zhou Z, Yang R, Zhang D, Xu M, Song J, Wang D, Li Y, Lei S, Zeng W, Yang Q, He P, Zhang Y, Zhou L, Cao L, Luo F, Liu H, Wang L, Ye F, Zhang M, Li M, Fan W, Li X, Li K, Ke B, Xu J, Yang H, He S, Pan M, Yan Y, Zha Y, Jiang L, Yu C, Liu Y, Xu Z, Li Q, Jiang Y, Sun J, Hong W, Wei H, Lu G, Vapalahti O, Luo Y, Wei Y, Connor T, Tan W, Snijder EJ, Smura T, Li W, Geng J, Ying B, Chen L. Lin JW, et al. Among authors: chen ss, chen l, chen c. Cell Host Microbe. 2021 Mar 10;29(3):489-502.e8. doi: 10.1016/j.chom.2021.01.015. Epub 2021 Jan 29. Cell Host Microbe. 2021. PMID: 33548198 Free PMC article.
Integrated single-cell RNA sequencing analysis reveals distinct cellular and transcriptional modules associated with survival in lung cancer.
Zhang L, Zhang Y, Wang C, Yang Y, Ni Y, Wang Z, Song T, Yao M, Liu Z, Chao N, Yang Y, Shao J, Li Z, Zhou R, Chen L, Zhang D, Zhao Y, Liu W, Li Y, He P, Lin JW, Wang Y, Zhang K, Chen L, Li W. Zhang L, et al. Among authors: chen l. Signal Transduct Target Ther. 2022 Jan 14;7(1):9. doi: 10.1038/s41392-021-00824-9. Signal Transduct Target Ther. 2022. PMID: 35027529 Free PMC article.
KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming.
Na F, Pan X, Chen J, Chen X, Wang M, Chi P, You L, Zhang L, Zhong A, Zhao L, Dai S, Zhang M, Wang Y, Wang B, Zheng J, Wang Y, Xu J, Wang J, Wu B, Chen M, Liu H, Xue J, Huang M, Gong Y, Zhu J, Zhou L, Zhang Y, Yu M, Tian P, Fan M, Lu Z, Xue Z, Zhao Y, Yang H, Zhao C, Wang Y, Han J, Yang S, Xie D, Chen L, Zhong Q, Zeng M, Lowe SW, Lu Y, Liu Y, Wei Y, Chen C. Na F, et al. Among authors: chen j, chen l, chen m, chen c, chen x. Nat Cancer. 2022 Jun;3(6):753-767. doi: 10.1038/s43018-022-00361-6. Epub 2022 Apr 21. Nat Cancer. 2022. PMID: 35449309 Free PMC article.
Targeting epigenetically maladapted vascular niche alleviates liver fibrosis in nonalcoholic steatohepatitis.
Zhang H, Ma Y, Cheng X, Wu D, Huang X, Chen B, Ren Y, Jiang W, Tang X, Bai T, Chen Y, Zhao Y, Zhang C, Xiao X, Liu J, Deng Y, Ye T, Chen L, Liu HM, Friedman SL, Chen L, Ding BS, Cao Z. Zhang H, et al. Among authors: chen l, chen b, chen y. Sci Transl Med. 2021 Oct 6;13(614):eabd1206. doi: 10.1126/scitranslmed.abd1206. Epub 2021 Oct 6. Sci Transl Med. 2021. PMID: 34613814
An Epigenetic Mechanism Underlying Chromosome 17p Deletion-Driven Tumorigenesis.
Chen M, Chen X, Li S, Pan X, Gong Y, Zheng J, Xu J, Zhao C, Zhang Q, Zhang S, Qi L, Wang Z, Shi K, Ding BS, Xue Z, Chen L, Yang S, Wang Y, Niu T, Dai L, Lowe SW, Chen C, Liu Y. Chen M, et al. Among authors: chen l, chen c, chen x. Cancer Discov. 2021 Jan;11(1):194-207. doi: 10.1158/2159-8290.CD-20-0336. Epub 2020 Sep 25. Cancer Discov. 2021. PMID: 32978226 Free PMC article.
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