Jinek M - Search Results

1

Key role of the REC lobe during CRISPR-Cas9 activation by 'sensing', 'regulating', and 'locking' the catalytic HNH domain.

Palermo G, Chen JS, Ricci CG, Rivalta I, Jinek M, Batista VS, Doudna JA, McCammon JA. Palermo G, et al. Among authors: jinek m. Q Rev Biophys. 2018;51:e91. doi: 10.1017/S0033583518000070. Epub 2018 Aug 3. Q Rev Biophys. 2018. PMID: 30555184 Free PMC article.

2

RNA-guided RNA silencing by an Asgard archaeal Argonaute.

Bastiaanssen C, Bobadilla Ugarte P, Kim K, Finocchio G, Feng Y, Anzelon TA, Köstlbacher S, Tamarit D, Ettema TJG, Jinek M, MacRae IJ, Joo C, Swarts DC, Wu F. Bastiaanssen C, et al. Among authors: jinek m. Nat Commun. 2024 Jun 29;15(1):5499. doi: 10.1038/s41467-024-49452-1. Nat Commun. 2024. PMID: 38951509 Free PMC article.

3

Enhancing prime editor activity by directed protein evolution in yeast.

Weber Y, Böck D, Ivașcu A, Mathis N, Rothgangl T, Ioannidi EI, Blaudt AC, Tidecks L, Vadovics M, Muramatsu H, Reichmuth A, Marquart KF, Kissling L, Pardi N, Jinek M, Schwank G. Weber Y, et al. Among authors: jinek m. Nat Commun. 2024 Mar 7;15(1):2092. doi: 10.1038/s41467-024-46107-z. Nat Commun. 2024. PMID: 38453904 Free PMC article.

4

Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47 ^phox -deficient chronic granulomatous disease.

Siow KM, Güngör M, Wrona D, Raimondi F, Pastukhov O, Tsapogas P, Menzi T, Schmitz M, Kulcsár PI, Schwank G, Schulz A, Jinek M, Modlich U, Siler U, Reichenbach J. Siow KM, et al. Among authors: jinek m. Mol Ther Nucleic Acids. 2024 May 24;35(3):102229. doi: 10.1016/j.omtn.2024.102229. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 38952440 Free PMC article.

5

A three-dimensional view of the molecular machinery of RNA interference.

Jinek M, Doudna JA. Jinek M, et al. Nature. 2009 Jan 22;457(7228):405-12. doi: 10.1038/nature07755. Nature. 2009. PMID: 19158786 Review.

6

Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense.

Wiedenheft B, Zhou K, Jinek M, Coyle SM, Ma W, Doudna JA. Wiedenheft B, et al. Among authors: jinek m. Structure. 2009 Jun 10;17(6):904-12. doi: 10.1016/j.str.2009.03.019. Structure. 2009. PMID: 19523907 Free article.

7

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation.

Jinek M, Fabian MR, Coyle SM, Sonenberg N, Doudna JA. Jinek M, et al. Nat Struct Mol Biol. 2010 Feb;17(2):238-40. doi: 10.1038/nsmb.1768. Epub 2010 Jan 24. Nat Struct Mol Biol. 2010. PMID: 20098421 Free PMC article.

8

Sequence- and structure-specific RNA processing by a CRISPR endonuclease.

Haurwitz RE, Jinek M, Wiedenheft B, Zhou K, Doudna JA. Haurwitz RE, et al. Among authors: jinek m. Science. 2010 Sep 10;329(5997):1355-8. doi: 10.1126/science.1192272. Science. 2010. PMID: 20829488 Free PMC article.

9

Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.

Weeks AM, Coyle SM, Jinek M, Doudna JA, Chang MC. Weeks AM, et al. Among authors: jinek m. Biochemistry. 2010 Nov 2;49(43):9269-79. doi: 10.1021/bi101102u. Biochemistry. 2010. PMID: 20836570 Free PMC article.

10

Coupled 5' nucleotide recognition and processivity in Xrn1-mediated mRNA decay.

Jinek M, Coyle SM, Doudna JA. Jinek M, et al. Mol Cell. 2011 Mar 4;41(5):600-8. doi: 10.1016/j.molcel.2011.02.004. Mol Cell. 2011. PMID: 21362555 Free PMC article.

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