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A single infusion of MDCO-216 (ApoA-1 Milano/POPC) increases ABCA1-mediated cholesterol efflux and pre-beta 1 HDL in healthy volunteers and patients with stable coronary artery disease.
Kallend DG, Reijers JA, Bellibas SE, Bobillier A, Kempen H, Burggraaf J, Moerland M, Wijngaard PL. Kallend DG, et al. Among authors: bobillier a. Eur Heart J Cardiovasc Pharmacother. 2016 Jan;2(1):23-9. doi: 10.1093/ehjcvp/pvv041. Epub 2015 Dec 11. Eur Heart J Cardiovasc Pharmacother. 2016. PMID: 27418968 Free PMC article. Clinical Trial.