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A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex.
Forrester A, De Leonibus C, Grumati P, Fasana E, Piemontese M, Staiano L, Fregno I, Raimondi A, Marazza A, Bruno G, Iavazzo M, Intartaglia D, Seczynska M, van Anken E, Conte I, De Matteis MA, Dikic I, Molinari M, Settembre C. Forrester A, et al. Among authors: iavazzo m. EMBO J. 2019 Jan 15;38(2):e99847. doi: 10.15252/embj.201899847. Epub 2018 Dec 17. EMBO J. 2019. PMID: 30559329 Free PMC article.
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B.
Cinque L, De Leonibus C, Iavazzo M, Krahmer N, Intartaglia D, Salierno FG, De Cegli R, Di Malta C, Svelto M, Lanzara C, Maddaluno M, Wanderlingh LG, Huebner AK, Cesana M, Bonn F, Polishchuk E, Hübner CA, Conte I, Dikic I, Mann M, Ballabio A, Sacco F, Grumati P, Settembre C. Cinque L, et al. Among authors: iavazzo m. EMBO J. 2020 Sep 1;39(17):e105696. doi: 10.15252/embj.2020105696. Epub 2020 Jul 27. EMBO J. 2020. PMID: 32716134 Free PMC article.
Sestrin2 drives ER-phagy in response to protein misfolding.
De Leonibus C, Maddaluno M, Ferriero R, Besio R, Cinque L, Lim PJ, Palma A, De Cegli R, Gagliotta S, Montefusco S, Iavazzo M, Rohrbach M, Giunta C, Polishchuk E, Medina DL, Di Bernardo D, Forlino A, Piccolo P, Settembre C. De Leonibus C, et al. Among authors: iavazzo m. Dev Cell. 2024 Aug 19;59(16):2035-2052.e10. doi: 10.1016/j.devcel.2024.07.004. Epub 2024 Aug 1. Dev Cell. 2024. PMID: 39094564 Free PMC article.