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Design, synthesis, and biologic evaluation of novel galloyl derivatives as HIV-1 RNase H inhibitors.
Gao P, Wang X, Sun L, Cheng X, Poongavanam V, Kongsted J, Álvarez M, Luczkowiak J, Pannecouque C, De Clercq E, Lee KH, Chen CH, Liu H, Menéndez-Arias L, Liu X, Zhan P. Gao P, et al. Among authors: luczkowiak j. Chem Biol Drug Des. 2019 Apr;93(4):582-589. doi: 10.1111/cbdd.13455. Epub 2019 Jan 24. Chem Biol Drug Des. 2019. PMID: 30560566 Free PMC article.
Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H,3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase.
Gao P, Cheng X, Sun L, Song S, Álvarez M, Luczkowiak J, Pannecouque C, De Clercq E, Menéndez-Arias L, Zhan P, Liu X. Gao P, et al. Among authors: luczkowiak j. Bioorg Med Chem. 2019 Sep 1;27(17):3836-3845. doi: 10.1016/j.bmc.2019.07.011. Epub 2019 Jul 6. Bioorg Med Chem. 2019. PMID: 31324562
Low-Valent Calix[4]arene Glycoconjugates Based on Hydroxamic Acid Bearing Linkers as Potent Inhibitors in a Model of Ebola Virus Cis-Infection and HCMV-gB-Recombinant Glycoprotein Interaction with MDDC Cells by Blocking DC-SIGN.
Chakroun K, Taouai M, Porkolab V, Luczkowiak J, Sommer R, Cheneau C, Mathiron D, Ben Maaouia MA, Pilard S, Abidi R, Mullié C, Fieschi F, Cragg PJ, Halary F, Delgado R, Benazza M. Chakroun K, et al. Among authors: luczkowiak j. J Med Chem. 2021 Oct 14;64(19):14332-14343. doi: 10.1021/acs.jmedchem.1c00818. Epub 2021 Sep 15. J Med Chem. 2021. PMID: 34524803
Detection of HIV-1 at between 20 and 49 copies per milliliter by the Cobas TaqMan HIV-1 v2.0 assay is associated with higher pretherapy viral load and less time on antiretroviral therapy.
Pascual-Pareja JF, Martínez-Prats L, Luczkowiak J, Fiorante S, Rubio R, Pulido F, Otero JR, Delgado R. Pascual-Pareja JF, et al. Among authors: luczkowiak j. J Clin Microbiol. 2010 May;48(5):1911-2. doi: 10.1128/JCM.02388-09. Epub 2010 Feb 24. J Clin Microbiol. 2010. PMID: 20181895 Free PMC article.
41 results