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260 results

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New insight into BRAF mutations in cancer.
Dhomen N, Marais R. Dhomen N, et al. Among authors: marais r. Curr Opin Genet Dev. 2007 Feb;17(1):31-9. doi: 10.1016/j.gde.2006.12.005. Curr Opin Genet Dev. 2007. PMID: 17208430 Review.
Oncogenic Braf induces melanocyte senescence and melanoma in mice.
Dhomen N, Reis-Filho JS, da Rocha Dias S, Hayward R, Savage K, Delmas V, Larue L, Pritchard C, Marais R. Dhomen N, et al. Among authors: marais r. Cancer Cell. 2009 Apr 7;15(4):294-303. doi: 10.1016/j.ccr.2009.02.022. Cancer Cell. 2009. PMID: 19345328 Free article.
BRAF signaling and targeted therapies in melanoma.
Dhomen N, Marais R. Dhomen N, et al. Among authors: marais r. Hematol Oncol Clin North Am. 2009 Jun;23(3):529-45, ix. doi: 10.1016/j.hoc.2009.04.001. Hematol Oncol Clin North Am. 2009. PMID: 19464601 Review.
Gatekeeper mutations mediate resistance to BRAF-targeted therapies.
Whittaker S, Kirk R, Hayward R, Zambon A, Viros A, Cantarino N, Affolter A, Nourry A, Niculescu-Duvaz D, Springer C, Marais R. Whittaker S, et al. Among authors: marais r. Sci Transl Med. 2010 Jun 9;2(35):35ra41. doi: 10.1126/scitranslmed.3000758. Sci Transl Med. 2010. PMID: 20538618
(V600E)Braf::Tyr-CreERT2::K14-Kitl mice do not develop superficial spreading-like melanoma: keratinocyte Kit ligand is insufficient to "translocate" (V600E)Braf-driven melanoma to the epidermis.
Rae J, Viros A, Hayward R, Bennett DC, Dhomen N, Longley BJ, Reis-Filho JS, Marais R. Rae J, et al. Among authors: marais r. J Invest Dermatol. 2012 Feb;132(2):488-91. doi: 10.1038/jid.2011.341. Epub 2011 Nov 24. J Invest Dermatol. 2012. PMID: 22113477 Free article. No abstract available.
Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma.
Girotti MR, Pedersen M, Sanchez-Laorden B, Viros A, Turajlic S, Niculescu-Duvaz D, Zambon A, Sinclair J, Hayes A, Gore M, Lorigan P, Springer C, Larkin J, Jorgensen C, Marais R. Girotti MR, et al. Among authors: marais r. Cancer Discov. 2013 Feb;3(2):158-67. doi: 10.1158/2159-8290.CD-12-0386. Epub 2012 Dec 14. Cancer Discov. 2013. PMID: 23242808 Free PMC article.
Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes.
Pedersen M, Küsters-Vandevelde HVN, Viros A, Groenen PJTA, Sanchez-Laorden B, Gilhuis JH, van Engen-van Grunsven IA, Renier W, Schieving J, Niculescu-Duvaz I, Springer CJ, Küsters B, Wesseling P, Blokx WAM, Marais R. Pedersen M, et al. Among authors: marais r. Cancer Discov. 2013 Apr;3(4):458-469. doi: 10.1158/2159-8290.CD-12-0464. Epub 2013 Jan 9. Cancer Discov. 2013. PMID: 23303902 Free PMC article.
260 results