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Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
Kumar P, Capodagli GC, Awasthi D, Shrestha R, Maharaja K, Sukheja P, Li SG, Inoyama D, Zimmerman M, Ho Liang HP, Sarathy J, Mina M, Rasic G, Russo R, Perryman AL, Richmann T, Gupta A, Singleton E, Verma S, Husain S, Soteropoulos P, Wang Z, Morris R, Porter G, Agnihotri G, Salgame P, Ekins S, Rhee KY, Connell N, Dartois V, Neiditch MB, Freundlich JS, Alland D. Kumar P, et al. Among authors: husain s. mBio. 2018 Dec 18;9(6):e02101-17. doi: 10.1128/mBio.02101-17. mBio. 2018. PMID: 30563908 Free PMC article.
A Novel Small-Molecule Inhibitor of the Mycobacterium tuberculosis Demethylmenaquinone Methyltransferase MenG Is Bactericidal to Both Growing and Nutritionally Deprived Persister Cells.
Sukheja P, Kumar P, Mittal N, Li SG, Singleton E, Russo R, Perryman AL, Shrestha R, Awasthi D, Husain S, Soteropoulos P, Brukh R, Connell N, Freundlich JS, Alland D. Sukheja P, et al. Among authors: husain s. mBio. 2017 Feb 14;8(1):e02022-16. doi: 10.1128/mBio.02022-16. mBio. 2017. PMID: 28196957 Free PMC article.
Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance.
Safi H, Gopal P, Lingaraju S, Ma S, Levine C, Dartois V, Yee M, Li L, Blanc L, Ho Liang HP, Husain S, Hoque M, Soteropoulos P, Rustad T, Sherman DR, Dick T, Alland D. Safi H, et al. Among authors: husain s. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19665-19674. doi: 10.1073/pnas.1907631116. Epub 2019 Sep 5. Proc Natl Acad Sci U S A. 2019. PMID: 31488707 Free PMC article.
Rapidly Correcting Frameshift Mutations in the Mycobacterium tuberculosis orn Gene Produce Reversible Ethambutol Resistance and Small-Colony-Variant Morphology.
Safi H, Lingaraju S, Ma S, Husain S, Hoque M, Soteropoulos P, Rustad T, Sherman DR, Alland D. Safi H, et al. Among authors: husain s. Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00213-20. doi: 10.1128/AAC.00213-20. Print 2020 Aug 20. Antimicrob Agents Chemother. 2020. PMID: 32571828 Free PMC article.
1,831 results