Wang Q - Search Results

1

Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma.

Wang Q, Dai Y, Ji Y, Shi H, Guo Z, Chen D, Chen Y, Peng X, Gao Y, Wang X, Chen L, Jiang Y, Geng M, Shen J, Ai J, Xiong B. Wang Q, et al. Among authors: wang x. Eur J Med Chem. 2019 Feb 1;163:671-689. doi: 10.1016/j.ejmech.2018.12.015. Epub 2018 Dec 7. Eur J Med Chem. 2019. PMID: 30572178

2

Design, synthesis and biological evaluation of gentiopicroside derivatives as potential antiviral inhibitors.

Wu S, Yang L, Sun W, Si L, Xiao S, Wang Q, Dechoux L, Thorimbert S, Sollogoub M, Zhou D, Zhang Y. Wu S, et al. Among authors: wang q. Eur J Med Chem. 2017 Apr 21;130:308-319. doi: 10.1016/j.ejmech.2017.02.028. Epub 2017 Feb 21. Eur J Med Chem. 2017. PMID: 28254701

3

Anti-acute myeloid leukemia activity of 2-chloro-3-alkyl-1,4-naphthoquinone derivatives through inducing mtDNA damage and GSH depletion.

Li K, Yang K, Zheng L, Li Y, Wang Q, Lin R, He D. Li K, et al. Among authors: wang q. Bioorg Med Chem. 2018 Aug 7;26(14):4191-4200. doi: 10.1016/j.bmc.2018.07.010. Epub 2018 Jul 7. Bioorg Med Chem. 2018. PMID: 30007564

4

Synthesis and cytotoxic studies of novel 5-phenylisatin derivatives and their anti-migration and anti-angiogenic evaluation.

Zhang Q, Teng Y, Yuan Y, Ruan T, Wang Q, Gao X, Zhou Y, Han K, Yu P, Lu K. Zhang Q, et al. Among authors: wang q. Eur J Med Chem. 2018 Aug 5;156:800-814. doi: 10.1016/j.ejmech.2018.07.032. Epub 2018 Jul 25. Eur J Med Chem. 2018. PMID: 30055465 Free PMC article.

5

Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia.

Guo Z, Zhang Z, Yang H, Cao D, Xu X, Zheng X, Chen D, Wang Q, Li Y, Li J, Du Z, Wang X, Chen L, Ding J, Shen J, Geng M, Huang X, Xiong B. Guo Z, et al. Among authors: wang x, wang q. J Med Chem. 2019 Jun 13;62(11):5414-5433. doi: 10.1021/acs.jmedchem.9b00297. Epub 2019 Jun 4. J Med Chem. 2019. PMID: 31117515

6

Chemical Fingerprint and Metabolic Profile Analysis of Tianshu Tablets by Ultra-High Performance Liquid Chromatography/Quadrupole-Time of Flight Mass Spectrometry.

Chen L, Chen R, Ouyang H, Wang Q, Li Z, Feng Y, Yang S. Chen L, et al. Among authors: wang q. J Anal Methods Chem. 2019 Oct 23;2019:9158942. doi: 10.1155/2019/9158942. eCollection 2019. J Anal Methods Chem. 2019. PMID: 31772816 Free PMC article.

7

BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies.

Berger M, Wortmann L, Buchgraber P, Lücking U, Zitzmann-Kolbe S, Wengner AM, Bader B, Bömer U, Briem H, Eis K, Rehwinkel H, Bartels F, Moosmayer D, Eberspächer U, Lienau P, Hammer S, Schatz CA, Wang Q, Wang Q, Mumberg D, Nising CF, Siemeister G. Berger M, et al. Among authors: wang q. J Med Chem. 2021 Sep 9;64(17):12723-12737. doi: 10.1021/acs.jmedchem.1c00762. Epub 2021 Aug 24. J Med Chem. 2021. PMID: 34428039 Free article.

8

Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis.

Dong Y, Tang BX, Wang Q, Zhou LW, Li C, Zhang X, Sun DD, Sun X, Zhang XM, Xiong B, Li J, Shi H, Chen DQ, Zang Y. Dong Y, et al. Among authors: wang q. Acta Pharmacol Sin. 2022 Jul;43(7):1769-1779. doi: 10.1038/s41401-021-00808-z. Epub 2021 Nov 24. Acta Pharmacol Sin. 2022. PMID: 34819618 Free PMC article.

9

HER2/PD1 bispecific antibody in IgG4 subclass with superior anti-tumour activities.

Chu W, Xu H, Wang Y, Xie Y, Chen YL, Tan X, Huang C, Wang G, Wang Q, Luo W, Xia N, Geng M, Xie Z, Wang C. Chu W, et al. Among authors: wang g, wang y, wang c, wang q. Clin Transl Med. 2022 Apr;12(4):e791. doi: 10.1002/ctm2.791. Clin Transl Med. 2022. PMID: 35384333 Free PMC article. No abstract available.

10

Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1H-pyrazol-4-yl) amino) quinazolin-6-yl)-N-(3-(trifluoromethyl) phenyl) benzamides as potent discoidin domain receptor inhibitors for the treatment of idiopathic pulmonary fibrosis.

Wang Q, Tang B, Sun D, Dong Y, Ji Y, Shi H, Zhou L, Yang Y, Luo M, Tan Q, Chen L, Dong Y, Li C, Xie R, Zang Y, Shen J, Xiong B, Li J, Chen D. Wang Q, et al. Acta Pharm Sin B. 2022 Apr;12(4):1943-1962. doi: 10.1016/j.apsb.2021.11.012. Epub 2021 Nov 17. Acta Pharm Sin B. 2022. PMID: 35847490 Free PMC article.

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